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This study will assess the effects of adalimumab treatment in moderate to severe Hidradenitis Suppurativa (HS) patients in the real world setting. The objectives of this study are to estimate the effectiveness of adalimumab treatment on disease severity, to estimate the impact of adalimumab treatment on patients' quality of life, psychological effect, work productivity and healthcare resource utilization and to describe treatment practices over the study period.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Participants receiving adalimumab | Hidradenitis Suppurativa (HS) participants receiving adalimumab |
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| Measure | Description | Time Frame |
|---|---|---|
| Proportion of participants with moderate to severe Hidradenitis Suppurativa (HS) who achieve a clinical response | Clinical response is evaluated by using the Hidradenitis Suppurativa clinical response measure (HiSCR) | At Week 12 |
| Measure | Description | Time Frame |
|---|---|---|
| Proportion of participants with moderate to severe HS who achieve a clinical response | Clinical response is evaluated by using the Hidradenitis Suppurativa clinical response measure (HiSCR) | Up to week 52 |
| Changes from baseline in Dermatology Quality of Life Index (DLQI) |
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Inclusion Criteria:
Exclusion Criteria:
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Hidradenitis Suppurativa (HS) participants receiving adalimumab
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| Name | Affiliation | Role |
|---|---|---|
| AbbVie Inc. | AbbVie | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Krankenanstalt Rudolfstiftung /ID# 166804 | Vienna | State of Vienna | 1030 | Austria | ||
| LKH-Univ. Klinikum Graz /ID# 166802 |
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| Label | URL |
|---|---|
| clinical study report synopsis | View source |
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Dermatology Life Quality Index (DLQI) score is a participant-reported outcome consisting of a set of 10 questions regarding the degree to which the participant's skin has affected certain behaviors and quality of life over the last week. Responses to each are: very much (score of 3), a lot, a little, or not at all (score of 0). The DLQI score ranges from 0 (best) to 30 (worst); the higher the score, the more quality of life is impaired. |
| From Week 0 to Week 52 |
| Graz |
| 8036 |
| Austria |
| Klinikum Wels - Grieskirchen /ID# 158017 | Wels | 4600 | Austria |
| UZ Brussel /ID# 154218 | Jette | Brussels Capital | 1090 | Belgium |
| Cliniques Universitaires Saint Luc /ID# 154217 | Woluwe-Saint-Lambert | Brussels Capital | 1200 | Belgium |
| CHU de Liege /ID# 154220 | Liège | Liege | 4000 | Belgium |
| UZ Gent /ID# 154221 | Ghent | Oost-Vlaanderen | 9000 | Belgium |
| CLIDERM Bruxelles /ID# 154232 | Anderlecht | 1070 | Belgium |
| PP Anderlecht /ID# 154230 | Anderlecht | 1070 | Belgium |
| CHIREC- City Clinic Louise /ID# 154227 | Brussels | 1000 | Belgium |
| ULB Erasme /ID# 154216 | Brussels | 1070 | Belgium |
| UZ Antwerp /ID# 154219 | Edegem | 2650 | Belgium |
| Boonen, Geel, BE /ID# 154233 | Geel | 2440 | Belgium |
| Coenen, Hasselt, BE /ID# 154234 | Hasselt | 3500 | Belgium |
| Polyclinique de Herstal /ID# 154226 | Herstal | 4040 | Belgium |
| Meuleman, Lede, BE /ID# 154238 | Lede | 9340 | Belgium |
| Grand Hopital de Charleroi /ID# 154222 | Loverval | 6280 | Belgium |
| Lanssens MD Maldegem BE /ID# 154237 | Maldegem | 9990 | Belgium |
| C.H.U.de Mons Borinage /ID# 154215 | Mons | 7000 | Belgium |
| Dr. Pierre-Dominique Ghislain, Mons, BE /ID# 154228 | Mons | 7000 | Belgium |
| CHU UCL Namur /ID# 154223 | Namur | 5000 | Belgium |
| CHU UCL Namur /ID# 154224 | Namur | 5000 | Belgium |
| Ctr Hosp du Bois de l'Abbaye /ID# 154235 | Seraing | 4100 | Belgium |
| Lecuyer, Thuin, Belgium /ID# 154229 | Thuin | 6530 | Belgium |
| AZ Sint-Rembert Ziekenhuis /ID# 154231 | Torhout | 8820 | Belgium |
| Centre Medical 4 sapins /ID# 154236 | Wavre | 1300 | Belgium |
| Sanatorium, s.r.o /ID# 163593 | Chotoviny | 391 32 | Czechia |
| Vojenska nemocnice /ID# 163592 | Olomouc | 779 00 | Czechia |
| Kozni sanatorium /ID# 163591 | Prague | 110 00 | Czechia |
| Kurzen, Freising, DE /ID# 153913 | Freising | 85354 | Germany |
| University General Hospital Attikon /ID# 156761 | Athens | Attica | 12462 | Greece |
| General Uni hosp of Larissa /ID# 156734 | Larissa | Thessaly | 415 00 | Greece |
| Duplicate_General Hospital of Athens Evaggelismos and Ophthalmiatrio of Athens P /ID# 156762 | Athens | 115 21 | Greece |
| 251 Airforce General Hospital /ID# 156731 | Athens | 11525 | Greece |
| Genl Hospital Andreas Syggros /ID# 156759 | Athens | 16121 | Greece |
| Genl Hospital Andreas Syggros /ID# 156760 | Athens | 16121 | Greece |
| University Gen Hosp of Patra /ID# 156735 | Pátrai | 26504 | Greece |
| General Hospital of Thessaloni /ID# 156728 | Thessaloniki | 55134 | Greece |
| General Hospital of Thessaloniki George Papanikolaou /ID# 156758 | Thessaloniki | 57010 | Greece |
| 401 GSNA - 401 Army Gen Hosp /ID# 156729 | Αthens | 11525 | Greece |
| Miskolci Semmelweis Korhaz es /ID# 153175 | Miskolc | Borsod-Abauj Zemplen county | 3529 | Hungary |
| Pecsi Tudomanyegyetem /ID# 152612 | Pécs | Pecs | 7624 | Hungary |
| Markusovszky Egyetemi Oktatókórház /ID# 152616 | Szombathely | Vas County | 9700 | Hungary |
| Semmelweis Egyetem /ID# 152613 | Budapest | 1085 | Hungary |
| Debreceni Egyetem Klinikai Központ /ID# 152615 | Debrecen | 4032 | Hungary |
| Somogy Megyei Kaposi Mor Oktat /ID# 160782 | Kaposvár | 7400 | Hungary |
| Bacs-Kiskun Megyei Korhaz /ID# 153180 | Kecskemét | 6000 | Hungary |
| Szegedi Tudomanyegyetem /ID# 152614 | Szeged | 6720 | Hungary |
| South Infirmary Victoria Univ /ID# 151095 | Cork | Ireland |
| St Vincent's University Hosp /ID# 151084 | Dublin | D04 T6F4 | Ireland |
| Adelaide and Meath Hosp,IE /ID# 151096 | Dublin | Ireland |
| Galway University Hospital /ID# 151097 | Galway | H91 YR71 | Ireland |
| University Hospital Waterford /ID# 153191 | Waterford | X91 ER8E | Ireland |
| Rabin Medical Center /ID# 149530 | Petakh Tikva | Tel Aviv | 4941492 | Israel |
| Tel Aviv Sourasky Medical Ctr /ID# 149528 | Tel Aviv | Tel Aviv | 6423906 | Israel |
| HaEmek Medical Center /ID# 164387 | Afula | 1834111 | Israel |
| Rambam Health Care Campus /ID# 149529 | Haifa | 3109601 | Israel |
| Hadassah University Hospital /ID# 149532 | Jerusalem | 91120 | Israel |
| Sheba Medical Center /ID# 149531 | Ramat Gan | 5262100 | Israel |
| Rizk Hospital /ID# 166027 | Beirut | 1100 | Lebanon |
| Saint Georges Hosp Med Cent /ID# 166024 | Beirut | 1100 | Lebanon |
| American Uni of Beirut Med Cen /ID# 166026 | Beirut | 1103 | Lebanon |
| Trad Hospital and Medical Cent /ID# 166025 | Beirut | 1103 | Lebanon |
| C/O Hotel Dieu de France /ID# 166028 | Beirut | Lebanon |
| General Hospital Celje /ID# 164673 | Celje | 3000 | Slovenia |
| Univ Medical Ctr Ljubljana /ID# 164671 | Ljubljana | 1000 | Slovenia |
| University Medical Ctr Maribor /ID# 164672 | Maribor | 2000 | Slovenia |
| GH Novo Mesto /ID# 164674 | Novo Mesto | 8000 | Slovenia |
| Hopitaux Universitaires de Geneve /ID# 160090 | Geneva | Canton of Geneva | 1205 | Switzerland |
| Inselspital, Universitaetsklinik /ID# 160089 | Bern | 3010 | Switzerland |
| University Hospital Zurich /ID# 160091 | Zurich | 8091 | Switzerland |
| Marmara University Med Faculty /ID# 157903 | Istanbul | 34662 | Turkey (Türkiye) |
| Whipps Cross Univ Hospital /ID# 150195 | London | London, City of | E11 1NR | United Kingdom |
| NHS Lanakshire (Monklands) /ID# 152885 | Airdire | ML6 0JS | United Kingdom |
| Belfast City Hospital /ID# 168411 | Belfast | BT9 7AB | United Kingdom |
| Univ Hospitals Birmingham NHS Foundation trust /ID# 152884 | Birmingham | B15 2TG | United Kingdom |
| Heartlands Hospital /ID# 168409 | Birmingham | B9 5SS | United Kingdom |
| Ninewells Hospital /ID# 168410 | Dundee | DD1 9SY | United Kingdom |
| Hull and East Yorkshire NHS /ID# 168413 | Hull | HU8 9HE | United Kingdom |
| St. James University Hospital /ID# 150200 | Leeds | LS9 7TF | United Kingdom |
| St. John's Institute of Dermat /ID# 150197 | London | SE1 9RT | United Kingdom |
| The Newcastle Upon Tyne Hospitals NHS Foundation Trust' /ID# 150199 | Newcastle upon Tyne | NE1 4LP | United Kingdom |
| Norfolk and Norwich Univ Hosp /ID# 168412 | Norwich | NR4 7UY | United Kingdom |
| ID | Term |
|---|---|
| D017497 | Hidradenitis Suppurativa |
| ID | Term |
|---|---|
| D017192 | Skin Diseases, Bacterial |
| D001424 | Bacterial Infections |
| D001423 | Bacterial Infections and Mycoses |
| D007239 | Infections |
| D012874 | Skin Diseases, Infectious |
| D013492 | Suppuration |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D016575 | Hidradenitis |
| D013543 | Sweat Gland Diseases |
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