Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Fecal impaction (FI) is a common cause of lower gastrointestinal tract obstruction, and it is the result of chronic or severe constipation and most commonly found in the elderly population. Gastrografin is a water soluble contrast mediate that could act as an osmotic laxative. It has been shown to confer a therapeutic benefit in adhesive small bowel obstruction (SBO). The investigators speculate that gastrografin administrated orally may be more effective than enema in the treatment of fecal impaction induced intestinal obstruction.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Exposure Group | Experimental | Participants were allocated to receive 100 mL of Gastrografin orally once daily for 6 consecutive days. |
|
| Control Group | Placebo Comparator | Participants were allocated to receive enemas twice daily for 6 consecutive days. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Gastrografin | Drug |
| ||
| enemas |
| Measure | Description | Time Frame |
|---|---|---|
| the proportion of patients having successful disimpaction | Successful disimpaction was indicated by the passage of watery stools. | 6 days |
| the time when patients having successful disimpaction | Successful disimpaction was indicated by the passage of watery stools. | 6 days |
| Measure | Description | Time Frame |
|---|---|---|
| Wexner constipation score | Severity of constipation symptoms was evaluated according to Wexner constipation scale. | 6 days |
| Patient Assessment of Constipation-Symptoms (PAC-SYM) score | Severity of constipation symptoms was evaluated according to PAC-SYM questionnaire. |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Ning Li, MD | Department of Generay Surgery, Jinling hosptal, Medical School of Nanjing University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Generay Surgery, Jinling hosptal, Medical School of Nanjing University | Nanjing | Jiangsu | 210002 | China |
Not provided
| ID | Term |
|---|---|
| D005244 | Fecal Impaction |
| ID | Term |
|---|---|
| D007415 | Intestinal Obstruction |
| D007410 | Intestinal Diseases |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
Not provided
Not provided
| ID | Term |
|---|---|
| D004733 | Enema |
| ID | Term |
|---|---|
| D004358 | Drug Therapy |
| D013812 | Therapeutics |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|
| 6 days |
| Patient Assessment of Constipation Quality of Life (PAC-QOL) score | Health-related quality of life was assessed using the trial by the PAC-QOL questionnaire. | 6 days |
| adverse events and safety | 6 days |