Response Based Treatment for Children With Unresectable Localized Soft Tissue Sarcoma

Response-based Treatment for Children With Unresectable Localized Soft Tissue Sarcomas

To evaluate the treatment outcome of unresectable soft tissue sarcoma using response based treatment

Response after initial chemotherapy is one of the important prognostic factor in many cancers. In this study, treatment will be tailored according to the treatment responses which are assessed by tumor volume reduction, necrosis rate or residual fludeoxyglucose (FDG) uptake in positron emission tomography (PET) scan.

Inclusion Criteria:

• Patients with unresectable localized high grade soft tissue sarcoma

Exclusion Criteria:

• Patients with organ dysfunction (ejection fraction, liver function test, creatinine > CTCAE grade 2)