Screening Latent Tuberculosis Infection and Observing Preventive Therapy in Kidney Transplantation

A Randomized Study for Screening Latent Tuberculosis Infection and Observing Preventive Therapy in Patients Preparing for Kidney Transplantation

Study the prevalence of LTBI in patients who are waiting renal transplant and monitor the incidence of active TB

Study the prevalence of LTBI in patients who are waiting renal transplant and monitor the incidence of active TB

Inclusion Criteria:

1. Age between 20-65 and match one of below
2. Waiting renal transplant or status post renal transplant
3. Receiving long term dialysis

Exclusion Criteria:

1. Not agree to be enrolled
2. Suspected active TB
3. HIV patients
4. Viral hepatitis
5. Using immunosuppressants within 3 months before enrollment
6. Receiving lymphokine therapy
7. Hemoglobin < 8 g/dL
8. Serum bilirubin > 2.5 mg/dL
9. AST or ALT > 2 times of upper normal limit
10. Lactation or pregnancy