Omega-3 Supplementation in Cervix Cancer Patients Undergoing Chemoradiotherapy

Effect of Omega-3 Supplementation on Body Composition, Functional Capacity, Inflammatory Profile and Quality of Life in Cervix Cancer Patients Undergoing Chemoradiotherapy

Cancer cachexia is a complex metabolic process affecting up to 80% of patients suffering from an advanced-stage cancer. Moreover, 20 to 40% of all cancer deaths are caused directly by cachexia. Recently, omega-3 fatty acids have gained interest for their beneficial effects in cancer cachexia. Moreover, nutritional supplementation enriched with omega-3 could potentially maintain body weight in cancer patients undergoing intensive treatment.

The investigators aims in this study is to evaluate the effect of omega-3 supplementation on body composition, functional capacity, inflammatory profile and quality of life in cervix cancer patients undergoing chemoradiotherapy.

Inclusion Criteria:

• Cervix cancer at FIGO stage II and III
• Chemoradiotherapy treatment proposal (cisplatin + radiotherapy)
• Nutritional diagnosis of pre-cachexia ou cachexia

Exclusion Criteria:

• metastasis (FIGO stage IV)
• Nutritional diagnosis of refractary cachexia