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The purpose of this study is to test an intervention designed to train persons who inject drugs (PWID) and are infected with hepatitis C (HCV) and HIV in communication skills to 1) promote new HCV treatment and care 2) risk reduction and 3) recruit their social network members for HIV and HCV testing and linkage to care.
The investigators propose recruiting 300 HIV/HCV co-infected PWID (i.e. Index participants). Half will be randomly assigned to the experimental condition and half to the equal attention comparison. The experimental intervention will include 8 group sessions that focus on communication to social network members, medical adherence and risk reduction skills, 2 dyad sessions with network members, monthly booster sessions for 6 months, and mHealth cuing of behavior for 6 months. These Index participants will be followed for 24 months (3, 6, 12, 18, & 24 month assessments). Participants who test positive for HCV will be linked to the Johns Hopkins Viral Hepatitis clinic to assess liver function and HCV chronicity and if applicable offered HCV treatment. Additionally, 450 network members will be recruited and will be tested for HIV and HCV and followed longitudinally to examine the social diffusion and social network factors associated with adherence among the Index participants.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Peer Mentor | Experimental | Individuals in this arm will be trained in communication skills to promote HIV and HCV testing to their social network members, linkage to care and risk reduction behaviors. |
|
| Neighborhood Matters | No Intervention | Participants in this arm will view a 15-20 minute video on issues in neighborhoods such as crime and violence, restoring communities and incarceration and discuss their reactions and thoughts. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Peer Mentor | Behavioral | comparison of communication training to equal attention control |
|
| Measure | Description | Time Frame |
|---|---|---|
| Continuity in HIV care scale | 24 months | |
| Access to HCV care scale | Initiation of HCV care at a viral hepatitis clinic | 24 months |
| Measure | Description | Time Frame |
|---|---|---|
| HIV medication adherence scale | 24 months |
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Inclusion Criteria:
Exclusion Criteria:
- participated in a behavioral intervention in prior 2 years
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| Name | Affiliation | Role |
|---|---|---|
| Carl A Latkin, PhD | Johns Hopkins Bloomberg School of Public Health | Principal Investigator |
| Karin E Tobin, PhD | Johns Hopkins Bloomberg School of Public Health | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Lighhouse Studies @ Peer Point | Baltimore | Maryland | 21205 | United States |
Will work with NIH to determine sharing plan
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| ID | Term |
|---|---|
| D006526 | Hepatitis C |
| D040242 | Risk Reduction Behavior |
| ID | Term |
|---|---|
| D000086982 | Blood-Borne Infections |
| D003141 | Communicable Diseases |
| D007239 | Infections |
| D006525 | Hepatitis, Viral, Human |
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| D014777 |
| Virus Diseases |
| D018178 | Flaviviridae Infections |
| D012327 | RNA Virus Infections |
| D006505 | Hepatitis |
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |
| D001519 | Behavior |