Midodrine During Recovery From Septic Shock

A Randomized Controlled Trial of Midodrine During Recovery Phase From Septic Shock

The purpose of this study is to determine whether midodrine administration decreases duration of intravenous vasopressors and intensive care unit length of stay for patients in septic shock.

Inclusion Criteria:

• admitted to intensive care unit
• diagnosis of septic shock on intravenous vasopressors
• stable/decreasing doses of intravenous vasopressors
• stable/improving organ function

Exclusion Criteria:

• allergy to midodrine
• multiple intravenous vasopressors
• increasing intravenous vasopressor requirements
• worsening organ dysfunction
• severe bradycardia