This study evaluates the feasibility of endo-laparoscopic full-thickness resection with simple suturing technique which did not expose gastric mucosa to peritoneum (simple non-exposure EFTR) in patients with gastric tumor.

Current endoscopic full-thickness resection (EFTR) methods are limited by their transmural communication and exposure of tumor to peritoneum. Recently, endo-laparoscopic full-thickness resection with simple suturing technique which did not expose gastric mucosa to peritoneum (simple non-exposure EFTR) was developed. This new technique includes the steps of laparoscopic seromuscular suturing with a barbed suture thread (V-Loc), which results in inversion of the stomach wall; EFTR of the inverted stomach wall from inside the stomach; and finally, endoscopic mucosal suturing with endoloops and clips.

This study evaluates the feasibility of simple non-exposure EFTR technique in patients with gastric tumor. This study is single arm study and will be performed in single center.

Inclusion Criteria:

• Gastric subepithelial tumor
• Tumor invades of muscularis propria on endoscopic ultrasonography (EUS) finding
• Tumor size more than 1.5cm or increasing size during observation

Exclusion Criteria:

• Tumor size more than 5cm
• Refuse to be enrolled to study.
• Bleeding tendency,
• Inappropriate condition for surgery with general anesthesia