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| Name | Class |
|---|---|
| King's College London | OTHER |
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This study aims to evaluate whether direct access from General Practitioners (GPs) to Magnetic Resonance Imaging (MRI) for patients with chronic headache decreases overall NHS costs and increases patient satisfaction compared to clinical practice with referral to Neurology Services.
Headache is the most common symptom reported in the community, affecting more than 90% of the population at some point in their lifetime. Despite the low level of referrals to secondary care (as most patients tend to be managed within primary care), the absolute number of headache episodes (due to its high prevalence) makes headache the most frequently listed reason for referral to the Neurologist and thus, utilises precious capacity that is severely constrained.
In order to support future management of this chronic condition, this study aims to evaluate existing clinical pathways in the management of patients with chronic headache - either referral to the Neurology Department or direct access to Imaging. Participants will be followed-up for a period of 12 months after the initial Secondary Care episode (either an MRI scan or Neurology appointment). Costs from the NHS perspective and self-perceived patient quality of life will be assessed and cost per patient and cost-effectiveness analyses will be performed.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| MRI scan | Direct referral from Primary Care (GPs) to an MRI scan as the initial Secondary Care point of contact. |
| |
| Neurology Appointment | Referral from Primary Care (GPs) to Neurology Services in Secondary Care as the initial Secondary Care point of contact. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| MRI scan | Other | MRI head scan to be performed as the first Secondary Care contact. |
| |
| Measure | Description | Time Frame |
|---|---|---|
| 6-month cost analysis per patient referred to either MRI or Neurology (measured in £ per patient) | The primary objective is to evaluate whether direct access from General Practitioners (GPs) to Magnetic Resonance Imaging (MRI) for patients with chronic headache is associated with cost-savings at 6 months after the initial episode at Secondary Care (either an MRI scan or a Neurology Outpatient appointment) compared to clinical practice with referral to the Neurology Department. | 6 months after the initial episode at Secondary Care (either an MRI scan or Neurology Outpatient appointment) |
| Measure | Description | Time Frame |
|---|---|---|
| 12-month cost analysis per patient referred to either MRI or Neurology (measured in £ per patient) | This secondary objective is aimed at evaluating whether direct access from General Practitioners (GPs) to Magnetic Resonance Imaging (MRI) for patients with chronic headache is associated with cost-savings at 12 months after the initial episode at Secondary Care (either an MRI scan or a Neurology Outpatient appointment) compared to clinical practice with referral to the Neurology Department. |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with chronic headache referred from Primary Care to Secondary Care to either an MRI scan or a Neurology outpatient appointment.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yvonne Akande, Master | Contact | yvonne.akande@kcl.ac.uk |
| Name | Affiliation | Role |
|---|---|---|
| Asif Mazumder, MD | Guy's and St Thomas' NHS Foundation Trust | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Guy's and St Thomas' NHS Foundation Trust | Recruiting | London | SE1 7EH | United Kingdom |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33067273 | Derived | Rua T, Mazumder A, Akande Y, Margariti C, Ochulor J, Turville J, Razavi R, Peacock JL, McCrone P, Goh V, Shearer J, Afridi S. Management of chronic headache with referral from primary care to direct access to MRI compared with Neurology services: an observational prospective study in London. BMJ Open. 2020 Oct 16;10(10):e036097. doi: 10.1136/bmjopen-2019-036097. |
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| ID | Term |
|---|---|
| D020773 | Headache Disorders |
| ID | Term |
|---|---|
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| ID | Term |
|---|---|
| D009682 | Magnetic Resonance Spectroscopy |
| ID | Term |
|---|---|
| D013057 | Spectrum Analysis |
| D002623 | Chemistry Techniques, Analytical |
| D008919 | Investigative Techniques |
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| Neurology Appointment |
| Other |
Outpatient appointment with Neurologist as the first Secondary Care contact |
|
| 12 months after the initial episode at Secondary Care (either an MRI scan or Neurology Outpatient appointment) |
| 6-month cost-effectiveness analysis per patient referred to either MRI or Neurology (measured in £ per QALY) | This secondary objective is aimed at evaluating whether direct access from General Practitioners (GPs) to Magnetic Resonance Imaging (MRI) for patients with chronic headache is cost-effective at 6 months after the initial episode at Secondary Care (either an MRI scan or a Neurology Outpatient appointment) compared to clinical practice with referral to the Neurology Department. | 6 months after the initial episode at Secondary Care (either an MRI scan or Neurology Outpatient appointment) |
| 12-month cost-effectiveness analysis per patient referred to either MRI or Neurology (measured in £ per QALY) | This secondary objective is aimed at evaluating whether direct access from General Practitioners (GPs) to Magnetic Resonance Imaging (MRI) for patients with chronic headache is cost-effective at 12 months after the initial episode at Secondary Care (either an MRI scan or a Neurology Outpatient appointment) compared to clinical practice with referral to the Neurology Department. | 12 months after the initial episode at Secondary Care (either an MRI scan or Neurology Outpatient appointment) |
| Patient satisfaction associated with both clinical pathways (direct referral to MRI or Neurology) | To evaluate and compare the levels of patient satisfaction associated with the two pathways: i) with direct access to MRI from Primary Care; and ii) with referral to the Neurology Department. A patient satisfaction questionnaire will be used to quantify patient satisfaction at 6 months. | 6 months |
| Patient's self perceived quality of life - measured using EQ-5D-5L questionnaire | This objective aims to evaluate the patient's self-perceived quality of life associated with both pathways using a standard questionnaire (EQ-5D-5L). | 6 months |
| Patient's self perceived quality of life - measured using HIT-6 questionnaire | This objective aims to evaluate the patient's self-perceived quality of life associated with both pathways using a standard headache-specific questionnaire (HIT-6 questionnaire). | 6 months |
| Patient's self perceived quality of life - measured using MIDAS questionnaire | This objective aims to evaluate the patient's self-perceived quality of life associated with both pathways using a standard headache-specific questionnaire (MIDAS questionnaire). | 6 months |
| Time-off work (measured in half days) due to chronic headache | To evaluate the headache burden and time-off work (both measured in half days) due to the chronic headache associated with the pathway with direct access to MRI compared with referral to the Neurology Department. | 12 months |