To assess the five-year incidence of AMD in a population from the central region of Portugal, previously phenotypically characterized.

Subjects who participated in the Epidemiologic Coimbra Eye Study (NCT01298674) between 2009 and 2013 will attend a single visit, after giving informed consent.

Inclusion Criteria:

• Subjects who participated in the Epidemiologic Coimbra Eye Study (NCT01298674) and that were phenotyped;
• Subjects capable of understanding the information about the study and to give their informed consent to enter the study;
• Subjects willing and able to comply with the study procedures.

Exclusion Criteria:

- Not applicable

The study population will consist of male and female subjects who have participated and phenotyped in the Epidemiologic Coimbra Eye Study (NTC01298674).

It is expected to recruit up to a total of 5.996 subjects, that is up to 2.975 subjects from the Mira Healthcare Unit and up to 3.021 subjects from the Lousã Healthcare Unit.