Hereditary Risk Factors for Thyroid Cancer
Hereditary Risk Factors for Thyroid Cancer
Thyroid cancers can occur sporadically, but can also be found as tumors that cluster in families with other cancers or genetic syndromes. Researchers are studying thyroid cancer in children and families, with a particular interest in understanding genes and other factors that may put individuals at risk for developing thyroid cancer and thyroid nodules.
The purpose of this research study is to learn more about risk factors for inherited thyroid cancer.
The investigators would like to use the participant DNA to look for alterations in genes. The investigator will perform DNA sequencing and other genetic studies to identify errors in the genes that may contribute to the formation of thyroid nodules and cancer.
Inclusion Criteria:
Individual pediatric patient with current or previous known or suspected thyroid cancer or nodule(s).
Individual adult patient with current or previous known or suspected thyroid cancer or nodule(s) if they come from a family with a high suspicion of hereditary cancer (as below).
Individuals from families with a high suspicion of hereditary thyroid cancer:
Families with a current or previous diagnosis of a thyroid cancer/nodule occurring in childhood (<18 years old).
Families with a high suspicion of hereditary thyroid cancer/nodules other than above to include:
Exclusion Criteria:
junne_kamihara@dfci.harvard.edu617.632.3044
sarah_hunt@dfci.harvard.edu