Evaluation of PSA Blood Levels Prior to and After Digital Rectal Examination

Evaluation of PSA Blood Levels in Men on Active Surveillance and Men With Benign Prostatic Hyperplasia Prior to and After Digital Rectal Examination

Patients with know prostate cancer (PCa) under active surveillance and aged matched controls without evidence of PCa will have a PSA blood test prior to and following standardized digital rectal examination

Patients with know prostate cancer (PCa) under active surveillance (Gleason 6, PSA < 10 ng/ml) and aged matched controls without evidence of PCa will have a PSA blood test prior to and following standardized digital rectal examination.

The change of PSA will be evaluated.

Inclusion Criteria:

• Males
• Intact Rectum
• Prostate Cancer eligible for active surveillance

Exclusion Criteria:

• Pror radiation therapy
• Under Androgen Deprivation Therapy
• Prior prostate surgery