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| ID | Type | Description | Link |
|---|---|---|---|
| R43NR015955 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Institute of Nursing Research (NINR) | NIH |
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This is a small trial to test feasibility of an idea for a potential device. The investigators tested the feasibility of prompting a volunteer to breathe when their breathing had slowed down during administration of anesthetic drugs.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Device prompting | Experimental |
| |
| Control | No Intervention | Patients receive standard of care |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Prompting breaths via recorded voice, vibrating massager, and/or muscle tetany | Device | Prompt volunteer to breathe using device to play recorded voice, massage the body, and/or apply muscle tetany |
| Measure | Description | Time Frame |
|---|---|---|
| Breath prompting successful rate | Change in respiratory rate from baseline to the period 10 seconds after the breath prompt |
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Inclusion Criteria:
Exclusion Criteria:
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39178322 | Derived | Farney RJ, Johnson KB, Ermer SC, Orr JA, Egan TD, Morris AH, Brewer LM. Quantified Ataxic Breathing Can Detect Opioid-Induced Respiratory Depression Earlier in Normal Volunteers Infused with Remifentanil. Anesth Analg. 2025 Sep 1;141(3):507-515. doi: 10.1213/ANE.0000000000007124. Epub 2024 Aug 23. | |
| 32287122 | Derived | Ermer SC, Farney RJ, Johnson KB, Orr JA, Egan TD, Brewer LM. An Automated Algorithm Incorporating Poincare Analysis Can Quantify the Severity of Opioid-Induced Ataxic Breathing. Anesth Analg. 2020 May;130(5):1147-1156. doi: 10.1213/ANE.0000000000004498. |
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| 30234539 | Derived | Ermer S, Brewer L, Orr J, Egan TD, Johnson K. Comparison of 7 Different Sensors for Detecting Low Respiratory Rates Using a Single Breath Detection Algorithm in Nonintubated, Sedated Volunteers. Anesth Analg. 2019 Aug;129(2):399-408. doi: 10.1213/ANE.0000000000003793. |