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To study the effect on decreasing chemotherapeutic toxicity and increasing anti-tumor treatment of Chinese Herbs based on syndrome differentiation
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Chemotherapy combined with compound herbal medicine | Experimental | Standard chemotherapy protocols on phase IIIB/IV non-small-cell lung cancer for 24 weeks combined with compound Chinese herbal medicine for 2 years,which include 15 kinds of Chinese herbs:Thunberg fritillary bulb,antimutangenic ,cimicifuga foetida,astragalus,pinellia ,Radix Ophiopogonis ,Solanum nigrum,Hedyotis diffusa,Prunella vulgaris ,cordate houttuynia,Herba Patriniae,dried orange peel ,Codonopsis,Wolfiporia extensa,Coix seed,Rhizoma Alismatis. |
|
| Chemotherapy | Active Comparator | The therapy of standard chemotherapy protocols on phase IIIB/IV non-small-cell lung cancer for 24 weeks |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| standard chemotherapy medicine combined with Chinese herbs | Drug |
| ||
| standard chemotherapy medicine |
| Measure | Description | Time Frame |
|---|---|---|
| Overall survival rate | 36months | |
| progression-free survival rate | 36months |
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| Measure | Description | Time Frame |
|---|---|---|
| Quality of Life Questionnaire (EORTC QLQ C30)scores | 36months | |
| RECIST(Response Evaluation Criteria In Solid Tumors) | 36months | |
| KPS scores |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Bao-guo Sun, doctor | Contact | 13316134352 | Sunbaoguo666@126.com | |
| Xin Zhou, master | Contact | 13533259616 | myeva520@163.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The First Affiliated Hospital of Sun-yat Sen University | Recruiting | Guangzhou | Guangdong | 510080 | China |
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| Drug |
|
| 36months |
| nutritional evaluation scores | 36months |
| BMS(Bone marrow suppression) scores | 36months |
| Gastrointestinal reactions scores | 36months |
| hair loss level scores | 36months |
| AST value | 36months |
| ALT value | 36months |
| creatinine value | 36months |
| ID | Term |
|---|---|
| D002289 | Carcinoma, Non-Small-Cell Lung |
| ID | Term |
|---|---|
| D002283 | Carcinoma, Bronchogenic |
| D001984 | Bronchial Neoplasms |
| D008175 | Lung Neoplasms |
| D012142 | Respiratory Tract Neoplasms |
| D013899 | Thoracic Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
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