The Effect on Decreasing Chemotherapeutic Toxicity and Increasing Anti-tumor Effect of Chinese Herbs Based on Syndrome Differentiation

To study the effect on decreasing chemotherapeutic toxicity and increasing anti-tumor treatment of Chinese Herbs based on syndrome differentiation

Inclusion Criteria:

• Histology and cytology diagnosed IIIB or IV non-small-cell lung cancer (NSCLC) and untreated; Age > 18 ages
• Sex unlimited; ECOG (Eastern Cooperative Oncology Group) fitness score (Performance status, PS)≤2.
• White blood cell count ≥ 3 x 10E9 / L, neutrophils ≥1 x 109 p/L, hemoglobin≥80 g/L , platelet ≥100 x 10E9 / L
• ALT, AST, normal or less than 2 times, bilirubin is normal
• Serum level in the normal range;Thr ecg is normal
• Expected survival time≥ 3 months or more;
• Agreed to the treatment combined traditional Chinese medicine with western medicine

Exclusion Criteria:

• Engaged in other clinical subjects
• Pregnant or lactating women, women in childbearing age refuse contraceptives during the trail
• Severe pneumonia, tuberculosis, lung abscess, myocarditis and other malignant tumor
• Severe damage of heart, liver and kidney (cardiac function grade 3 ~ 4, ALT and/or AST 2 times more than normal , Cr more the normal limit)
• Mental illness, Refused to partner; Cannot obtain informed consent