Tranexamic Acid in Hip Fracture Surgery

Effectiveness of Tranexamic Acid (TXA) in Reducing Blood Loss in Hip Fracture Surgery

To determine if TXA utilization is effective at reducing transfusion rates in elderly patients undergoing surgery for treatment of a hip fractures.

Inclusion Criteria:

• Acute, isolated, unilateral femoral neck, intertrochanteric, and per trochanteric hip fractures confirmed by anteroposterior/lateral hip radiographs, computed tomography, or magnetic resonance imaging.
• Age 65 and older
• Low energy mechanism of injury
• Hip fracture fixation performed within 48 hours
• English speaking
• Anticipated medical optimization for operative fixation
• No other major trauma

Exclusion Criteria:

• Retained hardware around the affected hip
• Infection around the affected hip
• Transfer patients with a length of stay > 24 hours at the transferring hospital
• Diagnosis of deficient natural anticoagulation
• Known congenital thrombophilia (Deficiency of Protein C, S, Antithrombin)
• Known allergy to TXA
• Patients undergoing percutaneous pinning of the hip fracture