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Delayed prescriptions have been shown to lower antibiotic use for upper respiratory tract infections (which are mostly viral).
This trial will test the hypothesis that if the clinician post-dates the delayed prescription by 2 days, rather than dating it on the day the patient is seen, there will be a further drop in the rate of antibiotic use.
6 family doctors and 2 nurse practitioners in a small rural town will issue delayed antibiotic prescriptions to adult patients with new acute respiratory tract infections. The delayed prescriptions will be randomly dated for either the day of the office visit, or 2 days later. The 2 local pharmacies will note whether the prescription is cashed, and when.
It is hypothesised that post-dating the prescription will result in a reduced cashing rate.
Each arm of the study (Usual v Post-Dated) will contain 75 subjects. This sample will have the power to detect a 25% change in prescription use.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Post-Dated Prescription | Other | a delayed prescription dated 2 days after clinical office visit |
|
| Usual | Other | usual date |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| A delayed prescription dated 2 days after clinical office visit | Other |
| ||
| Usual Dated |
| Measure | Description | Time Frame |
|---|---|---|
| Number of Participants That Filled a Prescription in 20 Days | Prescriptions | 20 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Memorial University | St. John's | Newfoundland and Labrador | A0G 2L0 | Canada |
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| ID | Title | Description |
|---|---|---|
| FG000 | Post-Dated Prescription | a delayed prescription dated 2 days after clinical office visit A delayed prescription dated 2 days after clinical office visit |
| FG001 | Usual | usual date Usual Dated |
| Title | Milestones | Reasons Not Completed | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Overall Study |
|
|
This was an ad hoc study, and therefore no baseline information was recorded for this study design
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| ID | Title | Description |
|---|---|---|
| BG000 | Post-Dated Prescription | a delayed prescription dated 2 days after clinical office visit A delayed prescription dated 2 days after clinical office visit |
| BG001 | Usual | usual date Usual Dated |
| Units | Counts |
|---|---|
| Participants |
|
| Title | Description | Population Description | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Denominator Units Selected | Denominators | Classes |
|---|---|---|---|---|---|---|---|---|---|
| Age, Categorical |
| Type | Title | Description | Population Description | Reporting Status | Anticipated Posting Date | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Time Frame | Units Analyzed | Denominator Units Selected | Arm/Group Information | Denominators | Classes | Analyses | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Primary | Number of Participants That Filled a Prescription in 20 Days | Prescriptions | Posted | Count of Participants | Participants | 20 days |
|
|
This study did not involve reporting of adverse reactions over the 19 days time span
This study was educational in nature. It was designed to just determine the timing of the number of the prescriptions filled by individuals. It is did not involve the gathering of any information on adverse effects.
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| ID | Title | Description | Deaths (Affected) | Deaths (At Risk) | Serious Events (Affected) | Serious Events (At Risk) | Other Events (Affected) | Other Events (At Risk) |
|---|---|---|---|---|---|---|---|---|
| EG000 | Post-Dated Prescription | a delayed prescription dated 2 days after clinical office visit A delayed prescription dated 2 days after clinical office visit |
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| Title | Organization | Phone | Extension | |
|---|---|---|---|---|
| Reza Tabrizchi | Memorial University | 706-864-3381 | rtabrizc@mun.ca |
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| ID | Term |
|---|---|
| D012141 | Respiratory Tract Infections |
| ID | Term |
|---|---|
| D007239 | Infections |
| D012140 | Respiratory Tract Diseases |
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| Drug |
|
| BG002 | Total | Total of all reporting groups |
|
| Sex: Female, Male |
|
| Race and Ethnicity Not Collected | Race and Ethnicity were not collected from any participant. |
| Participants |
|
|
|
| 0 |
| 0 |
| 0 |
| 0 |
| 0 |
| 0 |
| EG001 | Usual | usual date Usual Dated | 0 | 0 | 0 | 0 | 0 | 0 |
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