Study of MR-based IGRT for Prostate Cancer

Single-arm Phase II Study of MR(Magnetic Resonance Imaging)-Based Image-guided Radiotherapy for Prostate Cancer

MR (Magnetic Resonance Imaging) - based IGRT (image-guided radiotherapy) for patients with prostate carcinoma.

Single arm, phase II study, MR (Magnetic Resonance Imaging) - based IGRT (Image-guided radiotherapy) of prostate cancer.

Primary endpoint: Grade 2+ GI (gastrointestinal) and genitourinary (GU) toxicity after 2 years.

Inclusion Criteria:

• histologically proven prostate cancer
• indication for curative treatment
• ECOG performance scale 0-2
• Informed consent

Exclusion Criteria:

• contraindications for curative treatment
• age<18year
• previous pelvic radiotherapy or prostatic treatment like TURP (transurethral resection of prostate), HIFU (high intensity focused ultrasound)
• serious comorbidity leading to inability for IGRT (image-guided radiotherapy)
• contraindications for MRI (Magnetic Resonance Imaging)