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A recent publication answered the study question being asked
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Previous studies attempted to understand the dysphotopsia phenomenon by examining intraocular lens type, anterior capsule depth, iris-to-lens depth, lens refractive material, clear cornea incision wounds and anterior capsulorrhexis. However, there is limited literature in understanding haptic orientation and negative dysphotopsia; postulated theories and anecdotal reports relate to horizontal haptic orientation and the lateralization of rays such that light is received both in smaller width and anterior to the peripheral retina; however, no formal studies currently exist.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Vertical orientation of Haptic orientation | Other | The orientation of the IOL haptic will be implanted in the vertical position during routine cataract surgery |
|
| Horizontal orientation of Haptic orientation | Other | The orientation of the IOL haptic will be implanted in the horizontal position during routine cataract surgery |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Acrylic lens implantation | Device |
|
| Measure | Description | Time Frame |
|---|---|---|
| Presence of negative dysphotopsia after cataract surgery at 6 months | Presence of negative dysphotopsia in the vertical IOL placement compared to horizontal IOL placement | 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Presence of negative dysphotopsia after cataract surgery at 1 week | Presence of negative dysphotopsia in the vertical IOL placement compared to horizontal IOL placement | 1 week |
| Presence of negative dysphotopsia after cataract surgery at 1 month |
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Inclusion Criteria: Patients with bilateral cataracts that are visually significant meeting standard criteria for removal and select standard monofocal lens implantation.
Exclusion Criteria: Patients with any prior refractive surgery including prior cataract surgery, corneal ocular pathology, iris atrophy/damage, retinal or optic nerve pathology. Patients with history of peripheral vision loss. Patients selecting multifocal or toric lens implantation.
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| Name | Affiliation | Role |
|---|---|---|
| Howard D Guan, MD | Loma Linda University | Principal Investigator |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 22727295 | Background | Holladay JT, Zhao H, Reisin CR. Negative dysphotopsia: the enigmatic penumbra. J Cataract Refract Surg. 2012 Jul;38(7):1251-65. doi: 10.1016/j.jcrs.2012.01.032. | |
| 15899465 | Background | Narvaez J, Banning CS, Stulting RD. Negative dysphotopsia associated with implantation of the Z9000 intraocular lens. J Cataract Refract Surg. 2005 Apr;31(4):846-7. doi: 10.1016/j.jcrs.2004.08.059. |
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Presence of negative dysphotopsia in the vertical IOL placement compared to horizontal IOL placement
| 1 month |
| 21700100 | Background | Masket S, Fram NR. Pseudophakic negative dysphotopsia: Surgical management and new theory of etiology. J Cataract Refract Surg. 2011 Jul;37(7):1199-207. doi: 10.1016/j.jcrs.2011.02.022. |
| 20202539 | Background | Vamosi P, Csakany B, Nemeth J. Intraocular lens exchange in patients with negative dysphotopsia symptoms. J Cataract Refract Surg. 2010 Mar;36(3):418-24. doi: 10.1016/j.jcrs.2009.10.035. |
| 18812121 | Background | Osher RH. Negative dysphotopsia: long-term study and possible explanation for transient symptoms. J Cataract Refract Surg. 2008 Oct;34(10):1699-707. doi: 10.1016/j.jcrs.2008.06.026. |
| 24957929 | Background | Burke TR, Benjamin L. Sulcus-fixated intraocular lens implantation for the management of negative dysphotopsia. J Cataract Refract Surg. 2014 Sep;40(9):1469-72. doi: 10.1016/j.jcrs.2013.11.037. Epub 2014 Jun 20. |
| 15899464 | Background | Trattler WB, Whitsett JC, Simone PA. Negative dysphotopsia after intraocular lens implantation irrespective of design and material. J Cataract Refract Surg. 2005 Apr;31(4):841-5. doi: 10.1016/j.jcrs.2004.12.044. |
| 20362862 | Background | Cooke DL. Negative dysphotopsia after temporal corneal incisions. J Cataract Refract Surg. 2010 Apr;36(4):671-2. doi: 10.1016/j.jcrs.2010.01.004. |