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A comparative study is conducted on the patients with suspected coronary artery disease (CAD). The patient will undergo coronary angiography after a somatic symptom scale (SSS) survey is carried out combining with Patient Health Questionnaire (PHQ-9) and Generalized Anxiety Disorder 7-items (GAD-7). Patient is then treated according to the checklist score and coronary angiography result. The efficacy, sensitivity and specificity of the SSS checklist will be evaluated during following up.
The presentation of physical complaints such as chest discomfort suggestive of suspicious coronary artery disease (CAD) but remain unexplained after negative finding from coronary angiography represents one of the most frustrating and puzzling problems in clinical medicine.A comparative study is conducted on the patients with suspected coronary artery disease. A somatic symptom scale (SSS) survey is carried out combining with Patient Health Questionnaire (PHQ-9) and Generalized Anxiety Disorder 7-items (GAD-7). Patient is treated according to the checklist score and coronary angiography result. Three surveys will be re-conducted 2 weeks after treatment. The sensitivity and specificity of the SSS checklist will be evaluated during following up.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| with CAD and somatic symptom | Other | Patients with the coronary artery disease and with the somatization symptom, the investigators treat the patients according to the guideline for coronary artery disease and anti-somatic agents (Deanxit, Prozac according to the somatization type) |
|
| without CAD, with somatic symptom | Other | Only somatic symptom is presented, anti-somatic agents is prescribed (Deanxit, Prozac according to the somatization type) |
|
| without CAD, without somatic symptom | No Intervention | Have neither coronary artery disease nor somatic symptom, continue follow-up. | |
| with CAD, without somatic symptom | Other | Patient with the coronary artery disease, without the somatization symptom, the investigators treat the patients according to coronary artery disease treatment guideline including coronary artery stent implantation,medication according to the severity of stenosis of the coronary arteries. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Deanxit | Drug | we use Deanxit for the patient with anxiety |
|
| Measure | Description | Time Frame |
|---|---|---|
| The efficacy of somatization symptom score | observe the efficacy by the score of somatic symptom scale (SSS), Patient Health Questionnaire (PHQ-9), Generalized Anxiety Disorder 7-items (GAD-7) | 2 weeks after the first visit |
| Measure | Description | Time Frame |
|---|---|---|
| scale chest discomfort | observe if the chest discomfort no change, alleviate or disappear | 2 weeks after the first visit |
| The efficacy of Patient Health Questionnaire | observe the efficacy by the score of Patient Health Questionnaire (PHQ-9) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Mao Jialiang, Docter | Contact | 13311606283 | 68383477 | maoji@aliyun.com |
| Jiang Meng, Doctor | Contact | 13788912766 | 58752445 | jiangmeng0919@163.com |
| Name | Affiliation | Role |
|---|---|---|
| Mao Jialiang, Docter | Renji hosipital,Jiaotong University, School of Medicine | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Renji Hospital | Recruiting | Shanghai | China |
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| ID | Term |
|---|---|
| D017566 | Microvascular Angina |
| ID | Term |
|---|---|
| D000787 | Angina Pectoris |
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| ID | Term |
|---|---|
| C000851 | flupentixol, melitracen drug combination |
| D005473 | Fluoxetine |
| ID | Term |
|---|---|
| D011437 | Propylamines |
| D000588 | Amines |
| D009930 | Organic Chemicals |
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| Prozac | Drug | we use Prozac for the patient with depression |
|
|
| coronary artery disease treatment | Procedure | including medication, coronary artery stent implantation according to the severity of stenosis of the coronary arteries |
|
|
| 2 weeks after the first visit |
| The efficacy of Generalized Anxiety Disorder 7-items | observe the efficacy by the score of Generalized Anxiety Disorder 7-items (GAD-7) | 2 weeks after the first visit |
| D014652 |
| Vascular Diseases |