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Previous studies have shown that omega-3 fatty acid pills intake have beneficial effect on vascular health in overweight and/or hypertensive patients.
However, there is a lack of studies showing the effect of everyday consumption of omega-3 fatty acids enriched food (not pills) on lipid profile and microvascular reactivity in healthy population.
This study aimed to determine the effect of omega-3 enriched chicken eggs consumption on microvascular reactivity and lipid profile in young healthy subjects.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Omega-3 | Experimental | Intake of 3 omega-3 fatty acids enriched chicken eggs per day for three weeks. |
|
| Regular | Experimental | Intake of 3 regular chicken eggs per day for three weeks. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Omega-3 chicken eggs | Dietary Supplement | Intake of 3 omega-3 fatty acids enriched chicken eggs per day for three weeks. |
|
| Measure | Description | Time Frame |
|---|---|---|
| microvascular reactivity | Cutaneous microvascular blood flow will be measured by Laser Doppler Flowmetry in response to vascular occlusion (post occlusive reactive hyperaemia - PORH) and in response to iontophoresis of acetylcholine (ACh) (endothelium dependent vasodilation). | Three weeks |
| Measure | Description | Time Frame |
|---|---|---|
| lipid profile | Measurement of plasma cholesterol, HDL cholesterol, LDL cholesterol and triglycerides level. | Three weeks |
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Inclusion Criteria:
- healthy volunteers
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ana Stupin, MD, PhD | Contact | +385915134958 | anacavka@mefos.hr | |
| Ines Drenjancevic, MD, PhD | Contact | +385912241406 | ines.drenjancevic@mefos.hr |
| Name | Affiliation | Role |
|---|---|---|
| Ines Drenjancevic, MD, PhD | Faculty of Medicine, University of Osijek, Croatia | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Medicine Osijek, Laboratory for Clinical and Sport Physiology | Recruiting | Osijek | 31000 | Croatia |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26498129 | Background | Cavka A, Cosic A, Jukic I, Jelakovic B, Lombard JH, Phillips SA, Seric V, Mihaljevic I, Drenjancevic I. The role of cyclo-oxygenase-1 in high-salt diet-induced microvascular dysfunction in humans. J Physiol. 2015 Dec 15;593(24):5313-24. doi: 10.1113/JP271631. Epub 2015 Dec 7. |
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| Regular chicken eggs | Dietary Supplement | Intake of 3 regular chicken eggs per day for three weeks. |
|