Short Life Agents in Balanced Anesthesia on Obstructive Sleep Apnea Syndrome

Respiratory Impact of Short Life Agents Used in Balanced Anesthesia on Patients Suffering or Suspected of Obstructive Sleep Apnea (OSA) Syndrome

The investigators aim to assess the respiratory effect of short half-life agents in balanced anesthesia on patients suffering from non-treated or suspected obstructive sleep apnea syndrome (OSA) We will study the impact on OSA of a regimen of remifentanil-desflurane versus a regimen of fentanyl-sevoflurane. Each patient will undergo three respiratory portable polygraphies: the night before the surgery ; the first night following the surgery ; the third night following the surgery.

Inclusion Criteria:

• Physical status I - III
• Patient scheduled to undergo lower limb orthopedic surgery
• Patients known for non-treated obstructive sleep apnea or suspected of having an obstructive sleep apnea

Exclusion Criteria:

• Patients known for treated obstructive sleep apnea ;
• Severe respiratory disease (i.e., chronic obstructive pulmonary disease, asthma, pulmonary fibrosis);
• Severe cardiovascular disease
• Chronic use of opiates ≥ 30mg/j morphine eq.
• Chronic use of benzodiazepine
• Inability to consent
• Refusal