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In the current study, the investigators plan to expand the knowledge of Positron Emission Tomography/Magnetic Resonance (PET/MR) reliability by assessing the repeatability of fludeoxyglucose (FDG) standardized uptake values (SUV) measurements, as well as apparent diffusion coefficients (ADC) measurements, in a broad population of patients with malignant solid tumors.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| FDG-PET/CT and FDG-PET/MR | Experimental |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Fludeoxyglucose F 18 | Radiation |
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| |
| Measure | Description | Time Frame |
|---|---|---|
| Variability of repeated quantitative measures of FDG uptake as measured by SUVmax | -SUVmax is the maximum standardized uptake value (SUV) of the area of showing metabolic activity and this is used to show response | Completion of study (up to Day 7) |
| Variability of repeated quantitative measures of FDG uptake as measured by SUVpeak | -SUVpeak, which is defined as the average SUV within a 1 cubic cm volume within the region of the tumor with the highest metabolic activity | Completion of study (up to Day 7) |
| Repeatability of diffusion-weighted imaging on PET/MR as measured by difference in mean ADC |
| Completion of study (up to Day 7) |
| Repeatability of diffusion-weighted imaging on PET/MR as measured by differences in minimum ADC |
| Completion of study (up to Day 7) |
| Measure | Description | Time Frame |
|---|---|---|
| Evaluation of the ratio of SUVmax and ADCmin | Completion of study (up to Day 7) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Richard L Wahl, M.D. | Washington University School of Medicine | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Washington University School of Medicine | St Louis | Missouri | 63110 | United States |
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| Label | URL |
|---|---|
| Alvin J. Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine | View source |
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| ID | Term |
|---|---|
| D019788 | Fluorodeoxyglucose F18 |
| D049268 | Positron-Emission Tomography |
| D014057 | Tomography, X-Ray Computed |
| D008279 | Magnetic Resonance Imaging |
| ID | Term |
|---|---|
| D003847 | Deoxyglucose |
| D003837 | Deoxy Sugars |
| D002241 | Carbohydrates |
| D014055 | Tomography, Emission-Computed |
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| Positron Emission Tomography |
| Device |
|
|
| Computerized Tomography | Device |
|
|
| Magnetic Resonance Imaging | Device |
|
|
| D007090 |
| Image Interpretation, Computer-Assisted |
| D003952 | Diagnostic Imaging |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D007089 | Image Enhancement |
| D010781 | Photography |
| D011877 | Radionuclide Imaging |
| D014054 | Tomography |
| D003947 | Diagnostic Techniques, Radioisotope |
| D011856 | Radiographic Image Enhancement |
| D011859 | Radiography |
| D014056 | Tomography, X-Ray |