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| Name | Class |
|---|---|
| The Cleveland Clinic | OTHER |
| Ohio State University | OTHER |
| Washington University School of Medicine | OTHER |
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In this study the investigators will examine patients who have undergone unilateral ACL reconstruction surgery to determine which structural and functional characteristics of the knee two and ten years post reconstruction surgery, aspects of the original injury and repair, and patient characteristics are risk factors for osteoarthritis after ACL reconstruction surgery.
The purpose of this study is to identify risk factors for signs and symptoms of osteoarthritis two and ten year post ACL reconstruction from information available at the time of surgery. Hypothesis: Smoking status, older age, higher BMI, increased severity of cartilage injuries, increased meniscal resection, revision surgery, and incidence of additional arthroscopic procedures will result in more symptoms and signs of osteoarthritis at 10-year follow-up.
Primary outcome measures will be the joint space width measured on weight-bearing radiographs, as well as the pain subscale of the Knee Injury and Osteoarthritis Score (KOOS).
Secondary outcome measures will include the knee related quality of life subscale of the Knee Injury and Osteoarthritis Score (KOOS).
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| Measure | Description | Time Frame |
|---|---|---|
| Joint space width measured on weight-bearing radiographs | 10 years after ACL reconstruction surgery | |
| Pain subscale of the Knee Injury and Osteoarthritis Score (KOOS). | 10 years after ACL reconstruction surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Knee related quality of life subscale of the Knee Injury and Osteoarthritis Score (KOOS) | 10 years after ACL reconstruction surgery |
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Inclusion Criteria:
Exclusion Criteria:
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Participants enrolled in the Multicenter Orthopaedic Outcomes Network cohort by one of study site surgeons and meeting eligibility criteria
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| Name | Affiliation | Role |
|---|---|---|
| Kurt P Spindler, MD | Vanderbilt University / The Cleveland Clinic Foundation | Principal Investigator |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33793363 | Derived | MOON Group; Everhart JS, Jones MH, Yalcin S, Reinke EK, Huston LJ, Andrish JT, Cox CL, Flanigan DC, Kaeding CC, Magnussen RA, Obuchowski N, Parker RD, Pedroza AD, Sanders RA, Winalski CS, Spindler KP. The Clinical Radiographic Incidence of Posttraumatic Osteoarthritis 10 Years After Anterior Cruciate Ligament Reconstruction: Data From the MOON Nested Cohort. Am J Sports Med. 2021 Apr;49(5):1251-1261. doi: 10.1177/0363546521995182. |
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| ID | Term |
|---|---|
| D010003 | Osteoarthritis |
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
| D012216 | Rheumatic Diseases |
| D000070598 | Anterior Cruciate Ligament Injuries |
| D007718 | Knee Injuries |
| ID | Term |
|---|---|
| D003240 | Connective Tissue Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D007869 | Leg Injuries |
| D014947 | Wounds and Injuries |
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