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It is a multicenter, prospective, observational study of standard care. This study analyses the care of patients on long term effective anticoagulation therapy (ADELC) during a primary hip or knee arthroplasty.
The objectives of the study are to:
The main objective is to estimate the risks, adjusted and not, of postoperative complications associated to a long term anticoagulation by comparing patients under anticoagulation to a control group of patients having the same interventions but who are not under anticoagulation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ADELC | Cohort of patients on long term anticoagulation and undergoing a primary hip or knee replacement. |
| |
| CONTROL | Cohort of patients not on long term anticoagulation and undergoing a primary hip or knee replacement. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| anticoagulation | Drug | anticoagulation refers to any long term effective anticoagulation including antivitamin K, direct oral anticoagulants. Aspirin, clopidogrel are not included |
| Measure | Description | Time Frame |
|---|---|---|
| a composite criteria including the occurrence of one or more bleeding complications, major thrombotic events, or reoperation for any reason | up to 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| The length of hospital stay | this is a continuous outcome measured. It measures the number of days from date of entry to the date of hospital discharge | until end of study, an expected 12 months |
| The proportion of patients who are transfused during the hospitalization |
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Inclusion Criteria:
Exclusion Criteria:
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Patients on long term effective anticoagulation (ADELC) or not undergoing a primary hip or knee replacement
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hôpital Cochin | Recruiting | Paris | IDF | 75014 | France |
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| up to day 15 |
| The occurrence of a complication of grade 2 or more from Dindo and Clavien classification . | within 12 months |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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