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Assess whether high doses of ?-3 fatty acids added to standard treatment of patients with acute hearta failure, hypoalbuminemia and high inflammatory activity, promotes an increase in serum albumin
Assess whether high doses of ?-3 fatty acids added to standard treatment of patients with acute hearta failure, hypoalbuminemia and high inflammatory activity, promotes an increase in serum albumin
Assess the effect of high doses of ?-3 fatty acids added to standard treatment of patients with acute hearta failure, hypoalbuminemia and high inflammatory activity on:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention | Experimental | 4 daily capsules of polyunsaturated fatty acids omega-3, during 4 weeks. Each capsule contains: 460 mg eicosapentaenoic acid ethyl ester and 380 mg docosahexaenoic acid ethyl ester. |
|
| Control | Placebo Comparator | Capsules of similar appearance and flavor without active drug |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Polyunsaturated fatty acids omega-3 | Drug | 4 daily capsules of polyunsaturated fatty acids omega-3, during 4 weeks. Each capsule contains: 460 mg eicosapentaenoic acid ethyl ester and 380 mg docosahexaenoic acid ethyl ester. |
| Measure | Description | Time Frame |
|---|---|---|
| Serum albumin levels | Serum albumin levels in the fourth week | Four weeks |
| Measure | Description | Time Frame |
|---|---|---|
| C-reactive protein levels | C-reactive protein levels in the fourth week | Four weeks |
| NTproBNP levels | NTproBNP levels in the fourth week |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospital San Juan de la Cruz | Úbeda | Jaen | 23400 | Spain |
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| Placebo | Drug | 4 daily capsules of similar appearance and flavor without active ingredient |
|
|
| Four weeks |
| Combined event of death from any cause or readmission for heart failure | Combined event of death from any cause or readmission for heart failure within three months after randomization | Three months |
| ID | Term |
|---|---|
| D006333 | Heart Failure |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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