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The investigators group has piloted a 6-week psycho-educational program, Growing Resiliency And CouragE with Cancer™ (GRACE), that bring together a variety of strategies and experiences from an inter-professional perspective to mitigate distress among patients with an advanced cancer diagnosis. GRACE is a six-session, empirically anchored intervention emphasizing a Logotherapy (Existential Therapy) and Cognitive-Behavioral Therapy approach involving psycho-education and process-oriented experiences. The curriculum includes themes illustrated via PowerPoint slides with semi-structured delivery, video presentations, a variety of mindfulness meditation practices, and selected readings that serve to reflect and capture the theme for the week of the curriculum.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention Arm | Experimental | Patients in the intervention group will be provided with all programmatic materials (including copies of power point presentations, copies of reading texts, and audio CDs) and classes will be held in group format, with a maximum of 9 participants per group. Classes will meet weekly, in a group, and at a set time. All classes will be facilitated jointly by the two Co-PIs. All participants will complete surveys before class, during class, at the end of class, 1 month after the end of class, 6 months after the end of class and 1 year after the end of the class. Additionally, those randomized to the intervention group will be asked to attend a 1 time focus group 1 week after the end of the class. |
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| Control Arm | No Intervention | Patients in the control group will be asked to complete surveys at: baseline, 6 weeks after baseline (T1), and 1 month after T1. After T1, the control group will off study and will be permitted to attend the next available GRACE course. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Growing Resiliency And CouragE with Cancer™ (GRACE) | Other | GRACE is a 6 week curriculum which includes themes illustrated via PowerPoint slides with semi-structured delivery, video presentations, a variety of mindfulness meditation practices, and selected readings that serve to reflect and capture the theme for the week of the curriculum. |
| Measure | Description | Time Frame |
|---|---|---|
| GRACE's Impact on Existential Distress (measured by survey) | Baseline to 6 weeks after baseline |
| Measure | Description | Time Frame |
|---|---|---|
| GRACE's Impact on Existential Distress (measured by survey) | Baseline to 10 weeks after baseline | |
| GRACE's Impact on anxiety (measured by survey) | Baseline to 6 weeks after baseline | |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Arash Asher, MD | Cedars-Sinai Medical Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cedars Sinai Medical Center | Los Angeles | California | 90048 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37104871 | Derived | Asher A, Shirazipour CH, Capaldi JM, Kim S, Diniz M, Jones B, Wertheimer J. A 6-Week Program to Strengthen Resiliency Among Women With Metastatic Cancer: A Randomized Clinical Trial. Oncologist. 2023 Aug 3;28(8):e669-e682. doi: 10.1093/oncolo/oyad091. |
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| ID | Term |
|---|---|
| D001943 | Breast Neoplasms |
| D009362 | Neoplasm Metastasis |
| ID | Term |
|---|---|
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D001941 | Breast Diseases |
| D012871 | Skin Diseases |
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| GRACE's Impact on anxiety (measured by survey) |
| Baseline to 10 weeks after baseline |
| GRACE's Impact on depression (measured by survey) | Baseline to 6 weeks after baseline |
| GRACE's Impact on depression (measured by survey) | Baseline to 10 weeks after baseline |
| GRACE's Impact on hopelessness (measured by survey) | Baseline to 6 weeks after baseline |
| GRACE's Impact on hopelessness (measured by survey) | Baseline to 10 weeks after baseline |
| GRACE's Impact on loneliness (measured by survey) | Baseline to 6 weeks after baseline |
| GRACE's Impact on loneliness (measured by survey) | Baseline to 10 weeks after baseline |
| D017437 |
| Skin and Connective Tissue Diseases |
| D009385 | Neoplastic Processes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |