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| Name | Class |
|---|---|
| National Hospital of Odonto-Stomatology | OTHER |
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Patients visiting National Hospital of Odonto-Stomatology for treating periodontitis used a food supplement (lozenge) containing chicken egg antibody (IgY) against Porphyromonas gingivalis gingipains as an adjunct to conventional scaling and root planing (SRP). After 8 weeks the patients were examined against. Parameters including probing depth (PD), bleeding on probing (BOP), number of P. gingivalis in periodontal pockets were evaluated and compared to the control group that had used placebo lozenges.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Gingipain IgY | Experimental | Participants consume lozenges containing IgY against gingipains of Porphyromonas gingivalis |
|
| Placebo IgY | Placebo Comparator | Participants consume lozenges containing placebo IgY |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| lozenges containing IgY | Dietary Supplement | Patients consumed food supplement lozenges containing IgY after nonsurgical periodontal therapy |
|
| Measure | Description | Time Frame |
|---|---|---|
| Effect of anti-gingipain IgY on probing pocket depth of subjects with chronic periodontitis | Outcome measurement is probing pocket depth (PD) | 8 weeks |
| Effect of anti-gingipain IgY on bleeding on probing of subjects with chronic periodontitis | Outcome measurement is bleeding on probing (BOP) | 8 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Effect of anti-gingipain IgY on Porphyromonas gingivalis level of subjects with chronic periodontitis | Outcome measurement is P. gingivalis level in periodontal pockets | 8 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Thi Hong Minh Nguyen, Ph. D | National Hospital of Odonto-Stomatology | Principal Investigator |
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| ID | Term |
|---|---|
| D055113 | Chronic Periodontitis |
| D010518 | Periodontitis |
| ID | Term |
|---|---|
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
| D002908 | Chronic Disease |
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| Placebo IgY | Dietary Supplement | Placebo IgY |
|
| D020969 |
| Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |