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Cystic Fibrosis is a hereditary, chronic respiratory illness. Cystic Fibrosis leads to a progressive decline in lung function.
School-aged children with cystic fibrosis experience backpack carrying everyday. Backpack carrying induce a restrictive effect responsible for lower lung function. Respiratory muscle strength is also impaired.
No studies assessed aerobic capacities during children's gait while carrying a backpack.
The investigators hypothesized that backpack carrying will induce an acute decline in lung function in children with cystic fibrosis compared to healthy children. Investigators also hypothesized that aerobic capacities will be impaired.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cystic Fibrosis children | Experimental | Children with Cystic Fibrosis will experience lung function measurement while backpack carrying. Aerobic Capacities will also be assessed during treadmill gait. |
|
| Healthy Children | Active Comparator | Healthy Children will experience lung function measurement while backpack carrying. Aerobic Capacities will also be assessed during treadmill gait. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Backpack Carrying | Behavioral | A 12,5% of body weight backpack will be used for each measurement. Lung function will be assessed while carrying a double strap backpack, a mono shoulder backpack and without a backpack. |
| Measure | Description | Time Frame |
|---|---|---|
| Lung Function (Forced Vital Capacity) | Immediate assessment while standing |
| Measure | Description | Time Frame |
|---|---|---|
| Lung function (Forced Expiratory Volume in 1 second) | Immediate assessment while standing | |
| Respiratory Muscle Strength (MIP) | Maximal inspiratory pressure | Immediate assessment while standing |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Pascal Le Roux, MD | Le Havre Hospital | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Le Havre Hospital | Le Havre | 76290 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25584722 | Background | Vieira AC, Ribeiro F. Impact of backpack type on respiratory muscle strength and lung function in children. Ergonomics. 2015;58(6):1005-11. doi: 10.1080/00140139.2014.997803. Epub 2015 Jan 13. | |
| 26154227 | Background | Dockrell S, Simms C, Blake C. Schoolbag carriage and schoolbag-related musculoskeletal discomfort among primary school children. Appl Ergon. 2015 Nov;51:281-90. doi: 10.1016/j.apergo.2015.05.009. Epub 2015 Jun 11. |
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| ID | Term |
|---|---|
| D003550 | Cystic Fibrosis |
| D053120 | Respiratory Aspiration |
| ID | Term |
|---|---|
| D010182 | Pancreatic Diseases |
| D004066 | Digestive System Diseases |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
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| Respiratory Muscle Strength (MEP) | Maximal expiratory pressure | Immediate assessment while standing |
| Oxygen uptake (VO2) | During 12min treadmill gait |
| Ratio Ventilation/VO2 (Ventilation equivalent for oxygen) | Number of liters of air must be ventilated to consume 1 Liter of O2 | During 12min treadmill gait |
| Ratio Ventilation/VCO2 (Ventilation equivalent for carbon dioxide) | Number of liters of air must be ventilated to reject 1 Liter of CO2 | During 12min treadmill gait |
| Dyspnea (Borg Scale) | During 12min treadmill gait |
| 25789173 | Background | Thobani A, Alvarez JA, Blair S, Jackson K, Gottlieb ER, Walker S, Tangpricha V. Higher mobility scores in patients with cystic fibrosis are associated with better lung function. Pulm Med. 2015;2015:423219. doi: 10.1155/2015/423219. Epub 2015 Feb 18. |
| 24948040 | Background | Ramsey KA, Ranganathan S. Interpretation of lung function in infants and young children with cystic fibrosis. Respirology. 2014 Aug;19(6):792-9. doi: 10.1111/resp.12329. Epub 2014 Jun 19. |
| 24884656 | Background | Pastre J, Prevotat A, Tardif C, Langlois C, Duhamel A, Wallaert B. Determinants of exercise capacity in cystic fibrosis patients with mild-to-moderate lung disease. BMC Pulm Med. 2014 Apr 30;14:74. doi: 10.1186/1471-2466-14-74. |
| D030342 |
| Genetic Diseases, Inborn |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D007232 | Infant, Newborn, Diseases |
| D012120 | Respiration Disorders |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |