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Investigator will examined the diagnostic effect of the endometrial washing by saline. Because this technique more less painful and easier compared to endometrial curettage. Participants will separate into two groups. In study groups before endometrial curettage 5 cc saline infused to the endometrial cavity then aspirate and put into thin prep to examined. After this procedure routine endometrial curettage will be done. In control group only endometrial curettage will be done. Pathologic results of thin prep and curettage will compared.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Endometrial saline plus curettage | Experimental | 5 cc saline infused to the endometrial cavity and aspirated. Then routine endometrial curettage performed for same participant. |
|
| Endometrial curettage | Active Comparator | Only routine endometrial curettage performed |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Endometrial saline plus curettage | Procedure |
| ||
| Endometrial curettage |
| Measure | Description | Time Frame |
|---|---|---|
| Cervical cytological results according to Bethesda 2003 | for endometrial washing sample | 1 month |
| Endometrial hyperplasiz classification according to World Health Organization 2013 | for endometrial curretage sampling | 1 month |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Mehmet Baki Şentürk, MD | Contact | +90 541 773 71 76 | dr.baki77@gmail.com | |
| Çetin Kılıççı, MD | Contact | +90 505 644 94 85 | cetinkilicci@hotmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Zeynep Kamil Maternity and Pediatric Research and Training Hospital | Recruiting | Istanbul | 34668 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 19305334 | Result | Moschos E, Ashfaq R, McIntire DD, Liriano B, Twickler DM. Saline-infusion sonography endometrial sampling compared with endometrial biopsy in diagnosing endometrial pathology. Obstet Gynecol. 2009 Apr;113(4):881-887. doi: 10.1097/AOG.0b013e31819b3fc7. | |
| 25568988 | Result | Rotenberg O, Renz M, Reimers L, Doulaveris G, Gebb J, Goldberg GL, Dar P. Simultaneous endometrial aspiration and sonohysterography for the evaluation of endometrial pathology in women aged 50 years and older. Obstet Gynecol. 2015 Feb;125(2):414-423. doi: 10.1097/AOG.0000000000000631. |
| Label | URL |
|---|---|
| Related Info | View source |
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| Procedure |
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| 19509571 | Result | Bese T, Demirkiran F, Guralp O, Sanioglu C, Arvas M. Transtubal transport of carcinoma cells into the peritoneal cavity after saline infusion via transcervical route in patients with endometrial carcinoma. Int J Gynecol Cancer. 2009 May;19(4):682-5. doi: 10.1111/IGC.0b013e3181a48c7f. |
| Related Info | View source |
| Related Info | View source |
| ID | Term |
|---|---|
| D014591 | Uterine Diseases |
| ID | Term |
|---|---|
| D005831 | Genital Diseases, Female |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D000091662 | Genital Diseases |
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| ID | Term |
|---|---|
| D003475 | Curettage |
| ID | Term |
|---|---|
| D013514 | Surgical Procedures, Operative |
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