Evaluation of the 4th Generation QuantiFERON-TB Test (QFT-Plus) for the Detection of Tuberculosis Infection

Evaluation of the 4th Generation QuantiFERON-TB Test (QFT-Plus) for the Detection of Tuberculosis Infection

To compare the positivity rate of the investigational assay to the currently approved QuantiFERON-TB Gold In-Tube assay.

Low Risk and Known Risk Cohorts

Inclusion Criteria:

• Compensated and uncompensated members (current or future) of the Department of Veterans Affairs with no identified symptoms of active TB disease
• Age greater than 18 years or less than 80 years.

Exclusion Criteria:

• Currently taking therapy for active tuberculosis or latent TB infection for more than 14 days.