Study of PSMA-targeted 18F-DCFPyL PET/CT in the Evaluation of Patients With Renal Cell Carcinoma

Study of PSMA-targeted 18F-DCFPyL PET/CT in the Evaluation of Patients With Renal Cell Carcinoma

In this study the investigators aim to evaluate diagnostic utility of prostate-specific membrane antigen (PSMA)-targeted 18F-DCFPyL PET/CT in patients with renal cell carcinoma (RCC).

Inclusion Criteria:

• Clinically diagnosed or histologically proven stage II-IV renal cell carcinoma
• Completed staging evaluation with computed tomography (CT) or magnetic resonance imaging (MRI) of the chest, abdomen and pelvis ≤90 days prior to study enrollment

Exclusion Criteria:

• History of other malignancy diagnosed within the last 3 years (with the exception of low risk prostate cancer, ductal carcinoma in situ of the breast, squamous cell carcinoma or basal cell carcinoma of the skin)
• Administered a radioisotope within 5 physical half-lives prior to study enrollment
• Pregnancy ((as determined in accordance with the policies of the positron emission tomography (PET) center))
• Intention to enroll in a blinded therapeutic clinical trial following Positron emission tomography-computed tomography (PET/CT)