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Laparoscopic excision of endometriotic cysts is the main stream surgical intervention for treatment of endometriosis. However there is evidence that intervention may effect ovarian reserve by destruction of healthy ovarian tissue during surgery. Available evidence on the topic are contradictory and employed research methodology are diverse. There is need for an adequately powered research with proper methodology to assess actual effects of surgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Laparoscopic removal | Patients with endometrioma who will undergo laparoscopic removal of cysts. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Laparoscopic removal of cysts | Procedure | Women with endometrioma lesions will undergo laparoscopic removal. Cysts will be enucleated with blunt dissection of the cyst capsule and following traction, counter traction maneuver. Bipolar coagulation will be used sparsely and suturing will be the predominant choice for achieving bleeding control. |
| Measure | Description | Time Frame |
|---|---|---|
| Anti-Mullerian hormone levels | AMH (anti-mullerian hormone) levels will be measured before surgery and during various time points up to 1 year after the surgery | 1 year |
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Inclusion Criteria:
Exclusion Criteria:
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This study will recruit healthy women besides having endometrioma cysts who will undergo laparoscopic removal of such lesions.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Erkan Kalafat | Contact | ekalafat@ankara.edu.tr |
| Name | Affiliation | Role |
|---|---|---|
| Erkan Kalafat | Ankara University | Principal Investigator |
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| ID | Term |
|---|---|
| D004715 | Endometriosis |
| ID | Term |
|---|---|
| D005831 | Genital Diseases, Female |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
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Blood serum samples
|
| D000091662 | Genital Diseases |