Prophylactic Tamsulosin Use for Prevention of Post-Operative Urinary Retention

Prophylactic Tamsulosin Use for Prevention of Post-Operative Urinary Retention

This randomized open-label study will be comprised of 2 cohorts: one control group and one treatment group. The trial will be conducted as an open label randomized trial to evaluate the efficacy of tamsulosin in the prevention of post-operative urinary retention. The study will include pre- and post-surgical evaluations of patients including symptoms of urinary retention and any adverse effects contributable to the study medication.

Inclusion Criteria:

• Any male age 40 or older
• Scheduled to undergo one of the planned surgeries (thoracic, general, or urologic)
• Ability to give informed consent

Exclusion Criteria:

• Current use of alpha blocker
• Current use of a strong CYP 3A4 inhibitors
• Any allergy to tamsulosin, alpha-blocker medication class, or anaphylaxis allergy to sulfate containing medications
• Patients with any upcoming surgery for cataracts
• Currently enrolled in a clinical trial
• Inability to give informed consent