Retinoschisis is usually a rare self-limited disease and seldom shows progression. There a splitting of the neurosensory retina occurs usually in the inferior temporal. Patients usually have good visual acuity and are asymptomatic. Combination of an inner and outer layer hole is considered high risk factor for development of a schisis detachment. The most important differential diagnosis is an retinal detachment, since if misdiagnosed unnecessary treatment is provided. In clinical examination, both can appear very thin and transparent.

Therefore exact diagnosis of retinoschisis and retinal detachment has to be assessed and regular follow-up controls have to be conducted for sufficient recognition of progression.

Inclusion Criteria:

• Male or female, at least 18 years of age.
• Ophthalmoscopic evidence of RS or RD
• Written informed consent has been obtained.

Exclusion Criteria:

• Progression of retinal detachment or retinoschisis requiring surgical treatment
• Contraindication to pupil dilation, known allergy.

30 consecutive patients will be recruited for this study; 15 with Retinoschisis and 15 with retinal detachment