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This is a study to investigate the effect of Tulsi (Ocimum sanctum Linn.) on metabolic and biochemical parameters in young overweight and obese subjects. Thirty overweight/obese volunteers will be divided into two groups. The first group will receive no intervention. The second group will be supplemented with one capsule of Tulsi orally every morning and evening in empty stomach for 60 days. The metabolic parameters and liver enzymes will be evaluated before and after the intervention.
This is a randomized, parallel group, open label pilot study to investigate the effect of Tulsi (Ocimum sanctum Linn.) on metabolic and biochemical parameters in young overweight and obese subjects. Thirty overweight/obese volunteers will be divided into two groups. The first group will receive no intervention. The second group will be supplemented with one capsule of Tulsi orally every morning and evening in empty stomach for 60 days. The metabolic parameters and liver enzymes will be evaluated before and after the intervention.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Tulsi | Experimental | One capsule of Tulsi (Ocimum sanctum) orally, every morning and evening in empty stomach for 60 days regularly. |
|
| No Tulsi | No Intervention | No intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Tulsi(Ocimum sanctum Linn.) capsules | Drug |
|
| Measure | Description | Time Frame |
|---|---|---|
| Serum lipid profile | 60 days |
| Measure | Description | Time Frame |
|---|---|---|
| Fasting plasma glucose | 60 days | |
| Fasting plasma insulin | 60 days | |
| Serum liver enzymes |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Sushil Ch Mahapatra, MBBS, MD | All India Institute of Medical Sciences, Bhubaneswar | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| All India Institute of Medical Sciences, Bhubaneswar | Bhubaneswar | Odisha | 751019 | India |
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| ID | Term |
|---|---|
| D009765 | Obesity |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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| ID | Term |
|---|---|
| D002214 | Capsules |
| ID | Term |
|---|---|
| D004304 | Dosage Forms |
| D004364 | Pharmaceutical Preparations |
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| 60 days |
| Insulin resistance | Using homeostatic model assessment(HOMA2) | 60 days |
| Body mass index | 60 days |
| D001835 |
| Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |