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The purpose of this study is to determine whether positive lifestyle interventions (diet modification and smoking cessation) are effective in the prevention of gastric pre-cancer and cancer occurrences and reccurence of gastric cancer after endoscopic resection.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Lifestyle intervention | Active Comparator | A better lifestyle that are supposed to prevent gastric cancer occurrence are advised to patients. Measures includes dietary change and cessation of smoking and alcohol abuse. Behavioural and cognitive strategies from investigators are performed to patients to ensure adherence to established intervention. |
|
| No intervention | No Intervention | No meassures are taken to change life style of enrolled patients. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Active measures of lifestyle modification | Behavioral |
|
| Measure | Description | Time Frame |
|---|---|---|
| gastric caner occurrence | gastric cancer proved by gastroscopy biopsy | 4 years |
| Measure | Description | Time Frame |
|---|---|---|
| All cause mortality | 5 years | |
| gastric tissue DNA methylation change of selected genes | All patients have gastric biopsy through gastroscopy at the enrollment time and the last follow-up. DNA methylation status of selected genes are tested. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Lin Lu, MD | Shandong University | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Linyi People's Hospital affiliated to Shandong University | Linyi | Shandong | 276000 | China |
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| ID | Term |
|---|---|
| D013274 | Stomach Neoplasms |
| ID | Term |
|---|---|
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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Participants are assigned to lifestyle intervention group or the control group without lifestyle intervention.
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| 4 years |
| D004066 |
| Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |
| D013272 | Stomach Diseases |