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The aim of this study is to evaluate the possible immunologic effects of spirulina in children with beta thalassemia.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| patients | Experimental | thirty children with beta thalassemia major will receive oral spirulina (tablets=500 mg) for 3 months with a dose of 250 mg/kg/day (maximum dose 4 gm) |
|
| controls | No Intervention | thirty healthy children of matched age and sex |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Spirulina | Dietary Supplement |
|
| Measure | Description | Time Frame |
|---|---|---|
| cluster of differentiation (CD4/CD25) ratio | 3 months | |
| cluster of differentiation (CD33/CD11b/Lin) ratio | 3 months | |
| serum immunoglobulins levels | 3 months | |
| serum levels of interferon gamma | 3 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Mohamed R El-Shanshory, MD | professor of pediatrics- head of hematooncology unit of pediatric department- Tanta University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Medicine- Tanta University | Tanta | Gharbia Governorate | 0000 | Egypt |
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| ID | Term |
|---|---|
| D017086 | beta-Thalassemia |
| ID | Term |
|---|---|
| D013789 | Thalassemia |
| D000745 | Anemia, Hemolytic, Congenital |
| D000743 | Anemia, Hemolytic |
| D000740 | Anemia |
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| D006402 |
| Hematologic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
| D006453 | Hemoglobinopathies |
| D030342 | Genetic Diseases, Inborn |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |