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The aim of this study is to determine whether drinking plain water when mildly dehydrated benefits cognitive performance and mood. Volunteers undergo a dehydration protocol designed to result in minor dehydration. While some participants receive two 150ml drinks of water others do not. Differences in cognitive functioning are assessed.
As an essential nutrient, an inadequate intake of water has negative consequences: without a source of water death will occur in days. When Benton and Young (2015) reviewed the topic they concluded that in healthy adults, mild dehydration (in the range of a loss of 2% body mass) had been found to adversely influence mood and cognition. However, it is unclear at what degree of hypohydration these effects begin to emerge.
This study was designed to determine whether small changes in hydration, of the level that might occur on a day to day basis, influence cognition and mood. During a dehydration protocol (sitting in a room heated to 30 degrees for four hours) young adult participants receive either drink two 150ml cups of water or nothing. Effects on memory, attention and mood are monitored.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Drink water | Experimental | Participants will receive two 150ml drinks of water during the dehydration protocol |
|
| Drink nothing | No Intervention | Participants will drink nothing during the dehydration protocol |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Water | Dietary Supplement | Participants will receive two cups of 150ml plain water |
|
| Measure | Description | Time Frame |
|---|---|---|
| Episodic memory - list of 30 words | Participants listen to a list of 30 words presented using a tape recorder. The words are of similar difficulty and matched for the number of syllables and frequency with which they occur in English. The subjects are asked to recall and write down as many words as possible. The difference in the total number of words remembered from baseline (before the intervention) is analysed. | change from 0 to 180 minutes after the start of the dehydration protocol |
| Focused attention - Eriksen Flanker Task | The Arrow Flankers test measures the ability to direct attention and ignore peripheral information. Participants are required to indicate whether the middle arrow is pointing to the right or left by pressing the corresponding arrow on the keyboard. Either side of the central arrow are distractors. Both the average reaction times (in milliseconds) and accuracy are recorded. The difference in performance from baseline (before the intervention) is analysed. | change from 0 to 180 minutes after the start of the dehydration protocol |
| Measure | Description | Time Frame |
|---|---|---|
| Thirst (Participants rate their thirst) | Participants rate their thirst | change from 0 to 180 minutes after the start of the dehydration protocol |
| Measure | Description | Time Frame |
|---|---|---|
| Amount of weight lost due to dehydration protocol | participants will be weighed at the start and end of the dehydration protocol and % weight loss calculated | 180 minutes |
| Body temperature | Change in body temperature will be monitored throughout |
Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Swansea University | Swansea | West Glamorgan | SA2 8PP | United Kingdom |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26290294 | Background | Benton D, Young HA. Do small differences in hydration status affect mood and mental performance? Nutr Rev. 2015 Sep;73 Suppl 2:83-96. doi: 10.1093/nutrit/nuv045. | |
| 27510536 | Derived | Benton D, Jenkins KT, Watkins HT, Young HA. Minor degree of hypohydration adversely influences cognition: a mediator analysis. Am J Clin Nutr. 2016 Sep;104(3):603-12. doi: 10.3945/ajcn.116.132605. Epub 2016 Aug 10. |
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| ID | Term |
|---|---|
| D014867 | Water |
| ID | Term |
|---|---|
| D006878 | Hydroxides |
| D000468 | Alkalies |
| D007287 | Inorganic Chemicals |
| D000838 | Anions |
| D007477 |
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| 180 minutes |
| Urine Osmolality | Urine samples will be collected at the start and end of the procedure so that changes in osmolality can be measured. | 180 minutes |
| Ions |
| D004573 | Electrolytes |
| D010087 | Oxides |
| D017601 | Oxygen Compounds |