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Social cognition and interaction training (SCIT), a group-based treatment that aims to improve both processing social information and functioning, may be an effective treatment for enhancing the social skills of people with schizophrenia. This study will compare the effectiveness of Social cognition and interaction training (SCIT) versus treatment as usual (ETP) in helping people with schizophrenia improve their social cognition and social functioning so specially on negative symptoms. Many studies show a connection between negative symptom and social cognition in schizophrenia.
This is a multicenter (6 centers in France), randomized, controlled trial compared people aged 18 to 50 years with a diagnostic of schizophrenia according to the Diagnostic and Statistical manual of Mental disorders, 4th edition (DSM-IV-TR), the Social Cognition and Interaction Training (SCIT) program will be compared to an already validated neurocognitive remediation program : therapeutic education program (ETP) Social Cognition and Interaction Training (SCIT) is composed of three phases: emotion training, figuring out situations, and integration. Social Cognition and Interaction Training (SCIT) will be delivered by therapists in 20 weekly sessions over 5 months.
160 patients will be randomized as follows: - Arm1, experimental: Social Cognition and Interaction Training (SCIT): 30h with therapist, videos and photos exercises - Arm 2, control: therapeutic education program (ETP): 30h with therapist, only discussion between patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Social Cognition and Interaction Training (SCIT) | Experimental | SCIT Social cognition and interaction training program. |
|
| Therapeutic education program (ETP) | Active Comparator | Therapeutic education program |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Social Cognition and Interaction Training (SCIT) | Behavioral | A randomized, controled trial of social cognition and interaction training ( SCIT) for patients with schizophrenia Spectrum disorders |
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline in Scale of Assessment of Negative Symptoms | Improvement of negative symptoms of schizophrenia in patients who received Social Cognition and Interaction Training (SCIT) program compared to patients receiving a Therapeutic Education Program (ETP), equivalent in number, duration and rhythm of sessions | 40 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline in positive and negative symptoms scale (PANSS) | Scales for clinical and psychosocial functioning measurement | 40 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| FRANCK NICOLAS, PUPH | CH LE VINATIER | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre Hospitalier de Clermont de l'Oise | Clermont | OISE | 60607 | France |
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| ID | Term |
|---|---|
| D012559 | Schizophrenia |
| ID | Term |
|---|---|
| D019967 | Schizophrenia Spectrum and Other Psychotic Disorders |
| D001523 | Mental Disorders |
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| therapeutic education program (ETP) | Behavioral | usual treatment ,30 hours with therapist, only discussion between patients |
|