The purpose of this study is to investigate the curative effect of the length of the jejunum exclusion in gastric surgry for T2DM and metabolic syndrome,and to draft Scientific and reasonable operation parameters.

Currently, there is a growing evidence supports the efficacy of Roux-en-Y gastric bypass for the treatment of Type 2 diabetes mellitus. However,there still have a great controversy about the operation parameters. With randomized controlled trial, Patients of BMI>21kg/m2 with type 2 diabetes were randomly divided into two groups: short biliarypancreatic limb:50cm;long biliarypancreatic limb :100cm. The investigators followed-up 3,6,12,24 months of the change of BMI,FBG,HbA1c,Blood pressure,Blood fat after surgery.

Inclusion Criteria:

• Aged 20-65 years old
• History of diabetes is less than 15 years
• Fasting c-peptide≥1.6
• BMI≥21kg/m2；
• Ability to understand the nature of the procedure and willing to follow postoperative routine lifestyle and checkups

Exclusion Criteria:

• Psychological and mental disorders
• Serious important organs such as heart and lung disease cannot be tolerated surgery
• Complex history of abdominal surgery in the abdominal cavity adhesion
• Pregnancy or lactation

Ethics Committee of Daping Hospital