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The purpose of this study is to evaluate the efficacy and safety of a proprietary nutraceutical supplement in capsule form over 4 months in treating blood pressure in a group of chronic hypertensive subjects that are not receiving any pharmaceutical anti-hypertensive agents or other nutraceutical supplements.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cardiopressin | Experimental | A 5 capsule proprietary blend of herbal extracts and nutrients |
|
| Placebo | Placebo Comparator | A 5 capsule placebo matched in color and size to the Experimental supplement |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cardiopressin | Dietary Supplement |
| ||
| Placebo |
| Measure | Description | Time Frame |
|---|---|---|
| Blood Pressure | Reduction in systolic and diastolic blood pressure as measured by office readings and 24 hour ABM ( ambulatory blood pressure monitor) | 4 months |
| Measure | Description | Time Frame |
|---|---|---|
| Endothelial Function | Measured via Endopat | 4 months |
| Small arterial compliance | Measured via computerized arterial pulse wave analysis (CAPWA) |
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Inclusion Criteria
Exclusion Criteria
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| Name | Affiliation | Role |
|---|---|---|
| Mark Houston, MD, MS, MSc | Hypertension Institute | Principal Investigator |
| Bodi Zhang, MD, MPH, PhD | Thorne Research | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hypertension Institute of Nashville, TN | Nashville | Tennessee | 37205 | United States |
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| ID | Term |
|---|---|
| D006973 | Hypertension |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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|
| 4 months |
| Large arterial compliance | Measured via computerized arterial pulse wave analysis (CAPWA) | 4 months |
| Central arterial blood pressure | Measured via computerized arterial pulse wave analysis (CAPWA) | 4 months |