The Effect of a Natural Extract on Glucose Fluxes After Consumption of a Wheat Product

The Effect of a Natural Extract on Glucose Fluxes After Consumption of a Wheat Product

This study is to quantify the effect of a natural fruit extract added to a wheat product on the time needed to absorb 50% of the apparent total of available exogenous carbohydrate (RaE * Time). In addition the different glucose fluxes will be quantified (RaE, EGP and GCR)

Inclusion Criteria:

• Healthy Caucasian male.
• Body mass index (BMI) ≥ 18.0 and ≤ 25.0 kg/m2.
• Apparently healthy: no medical conditions which might affect the study measurements including diabetes type 1 and type 2, gastrointestinal dysfunction, gastrointestinal surgery and inflammatory diseases.
• Fasting blood glucose value of volunteer is ≥ 3.4 and ≤ 6.1 mmol/liter (i.e. 62- 110 mg/dl) at screening.
• HbA1c ≤ 6.5 % (48 mmol/mol).

Exclusion Criteria:

• Use of antibiotics within 3 months before Day 1; use of any other medication except paracetamol within 14 days before Day 1.