Peripheral Blood Biomarkers Associated With CIPN

Investigation of Peripheral Blood Biomarkers Associated With CIPN

The investigators are doing a research study that will teach us about the tingly pain that people develop when they get chemotherapy.

The investigators are asking for a blood sample, information about patients symptoms during chemotherapy, and past medical history from people who have taken or will take certain types of chemotherapy. The investigators hope to examine blood for proteins that could help us learn which patients get neurological symptoms while getting chemotherapy. The investigators' main research goal is to improve the treatment of patients getting chemotherapy to help their quality of life and/or help to increase the chance of their cancer being cured.

Inclusion Criteria:

• Diagnosis of a tumor for which Platinums, Vinca Alkaloids, Bortezomib or Taxanes are indicated
• No prior history of diabetic, anatomical or regional neuropathies (except pre-existing CIPN)
• Age ≥ 18 years
• Capable of understanding the investigational nature, potential risks and benefits of the study, and able to provide valid informed consent.

Exclusion Criteria:

• Inability to give consent
• Inability to tolerate venipuncture for any reason
• Age < 18 years
• Any known medical, surgical or psychiatric condition that may interfere with the conduct of the study or be detrimental to the donor in the opinion of the PI or caring physician
• Consent Refusal by patient