| Primary | Change From Baseline in Best Corrected Visual Acuity (BCVA) Total Letters Score at Month 1- Treated Eye | Best corrected visual acuity (BCVA) was assessed in the study eye (Treated eye). BCVA measurements were made using the logarithm of the minimum angle of resolution (logMAR) visual acuity testing charts. Each letter on the chart has a score value of 0.02 log units. Since there were 5 letters per line, the total score for a line on the logMAR chart represented a change of 0.1 log units. The formula for calculating the logMAR BCVA score was: 1.7 - 0.02*number of letters read. A lower BCVA score indicates better vision. A negative change score indicates improvement. | The safety analysis set defined as participants who were enrolled and received surgery in the study. | Posted | | Mean | Standard Deviation | logMAR | | Baseline and Month 1 | | | | ID | Title | Description |
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| OG000 | CNTO 2476 3.0*10^5 Cells | Participants received a single subretinal administration of CNTO 2476 (Palucorcel) comprising 3.0*10^5 cells in 50 microliters (mcL) dosing volume on Day 1. CNTO 2476 was delivered using the custom-designed Delivery System and surgical procedure. |
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| Primary | Change From Baseline in Best Corrected Visual Acuity Total Letters Score at Month 2- Treated Eye | BCVA was assessed in the study eye (Treated eye). BCVA measurements were made using the logMAR visual acuity testing charts. Each letter on the chart has a score value of 0.02 log units. Since there were 5 letters per line, the total score for a line on the logMAR chart represented a change of 0.1 log units. The formula for calculating the logMAR BCVA score was: 1.7 - 0.02*number of letters read. A lower BCVA score indicates better vision. A negative change score indicates improvement. | The safety analysis set defined as participants who were enrolled and received surgery in the study. | Posted | | Mean | Standard Deviation | logMAR | | Baseline and Month 2 | | | | ID | Title | Description |
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| OG000 | CNTO 2476 3.0*10^5 Cells | Participants received a single subretinal administration of CNTO 2476 (Palucorcel) comprising 3.0*10^5 cells in 50 microliters (mcL) dosing volume on Day 1. CNTO 2476 was delivered using the custom-designed Delivery System and surgical procedure. |
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| Primary | Change From Baseline in Best Corrected Visual Acuity Total Letters Score at Month 3- Treated Eye | BCVA was assessed in the study eye (Treated eye). BCVA measurements were made using the logMAR visual acuity testing charts. Each letter on the chart has a score value of 0.02 log units. Since there were 5 letters per line, the total score for a line on the logMAR chart represented a change of 0.1 log units. The formula for calculating the logMAR BCVA score was: 1.7 - 0.02*number of letters read. A lower BCVA score indicates better vision. A negative change score indicates improvement. | The safety analysis set defined as participants who were enrolled and received surgery in the study. | Posted | | Mean | Standard Deviation | logMAR | | Baseline and Month 3 | | | | ID | Title | Description |
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| OG000 | CNTO 2476 3.0*10^5 Cells | Participants received a single subretinal administration of CNTO 2476 (Palucorcel) comprising 3.0*10^5 cells in 50 microliters (mcL) dosing volume on Day 1. CNTO 2476 was delivered using the custom-designed Delivery System and surgical procedure. |
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| Primary | Change From Baseline in Best Corrected Visual Acuity Total Letters Score at Month 6- Treated Eye | BCVA was assessed in the study eye (Treated eye). BCVA measurements were made using the logMAR visual acuity testing charts. Each letter on the chart has a score value of 0.02 log units. Since there were 5 letters per line, the total score for a line on the logMAR chart represented a change of 0.1 log units. The formula for calculating the logMAR BCVA score was: 1.7 - 0.02*number of letters read. A lower BCVA score indicates better vision. A negative change score indicates improvement. | The safety analysis set defined as participants who were enrolled and received surgery in the study. | Posted | | Mean | Standard Deviation | logMAR | | Baseline and Month 6 | | | | ID | Title | Description |
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| OG000 | CNTO 2476 3.0*10^5 Cells | Participants received a single subretinal administration of CNTO 2476 (Palucorcel) comprising 3.0*10^5 cells in 50 microliters (mcL) dosing volume on Day 1. CNTO 2476 was delivered using the custom-designed Delivery System and surgical procedure. |
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| Primary | Change From Baseline in Best Corrected Visual Acuity Total Letters Score at Month 12- Treated Eye | BCVA was assessed in the study eye (Treated eye). BCVA measurements were made using the logMAR visual acuity testing charts. Each letter on the chart has a score value of 0.02 log units. Since there were 5 letters per line, the total score for a line on the logMAR chart represented a change of 0.1 log units. The formula for calculating the logMAR BCVA score was: 1.7 - 0.02*number of letters read. A lower BCVA score indicates better vision. A negative change score indicates improvement. | The safety analysis set defined as participants who were enrolled and received surgery in the study. Here, N (number of participants analyzed) signifies number of participant evaluable for this endpoint. | Posted | | Mean | Standard Deviation | logMAR | | Baseline and Month 12 | | | | ID | Title | Description |
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| OG000 | CNTO 2476 3.0*10^5 Cells | Participants received a single subretinal administration of CNTO 2476 (Palucorcel) comprising 3.0*10^5 cells in 50 microliters (mcL) dosing volume on Day 1. CNTO 2476 was delivered using the custom-designed Delivery System and surgical procedure. |
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| Primary | Change From Baseline in Best Corrected Visual Acuity Total Letters Score at Month 18- Treated Eye | BCVA was assessed in the study eye (Treated eye). BCVA measurements were made using the logMAR visual acuity testing charts. Each letter on the chart has a score value of 0.02 log units. Since there were 5 letters per line, the total score for a line on the logMAR chart represented a change of 0.1 log units. The formula for calculating the logMAR BCVA score was: 1.7 - 0.02*number of letters read. A lower BCVA score indicates better vision. A negative change score indicates improvement. | The safety analysis set defined as participants who were enrolled and received surgery in the study. Here, N (number of participants analyzed) signifies number of participant evaluable for this endpoint. | Posted | | Mean | Standard Deviation | logMAR | | Baseline and Month 18 | | | | ID | Title | Description |
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| OG000 | CNTO 2476 3.0*10^5 Cells | Participants received a single subretinal administration of CNTO 2476 (Palucorcel) comprising 3.0*10^5 cells in 50 microliters (mcL) dosing volume on Day 1. CNTO 2476 was delivered using the custom-designed Delivery System and surgical procedure. |
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| Primary | Change From Baseline in Best Corrected Visual Acuity (BCVA) Total Letters Score at Month 24- Treated Eye | BCVA was assessed in the study eye (Treated eye). BCVA measurements were made using the logMAR visual acuity testing charts. Each letter on the chart has a score value of 0.02 log units. Since there were 5 letters per line, the total score for a line on the logMAR chart represented a change of 0.1 log units. The formula for calculating the logMAR BCVA score was: 1.7 - 0.02*number of letters read. A lower BCVA score indicates better vision. A negative change score indicates improvement. | The safety analysis set defined as participants who were enrolled and received surgery in the study. Here, N (number of participants analyzed) signifies number of participant evaluable for this endpoint. | Posted | | Mean | Standard Deviation | logMAR | | Baseline and Month 24 | | | | ID | Title | Description |
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| OG000 | CNTO 2476 3.0*10^5 Cells | Participants received a single subretinal administration of CNTO 2476 (Palucorcel) comprising 3.0*10^5 cells in 50 microliters (mcL) dosing volume on Day 1. CNTO 2476 was delivered using the custom-designed Delivery System and surgical procedure. |
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| Primary | Change From Baseline in Best Corrected Visual Acuity (BCVA) Total Letters Score at Month 30- Treated Eye | BCVA was assessed in the study eye (Treated eye). BCVA measurements were made using the logMAR visual acuity testing charts. Each letter on the chart has a score value of 0.02 log units. Since there were 5 letters per line, the total score for a line on the logMAR chart represented a change of 0.1 log units. The formula for calculating the logMAR BCVA score was: 1.7 - 0.02*number of letters read. A lower BCVA score indicates better vision. A negative change score indicates improvement. | The safety analysis set defined as participants who were enrolled and received surgery in the study. Here, N (number of participants analyzed) signifies number of participant evaluable for this endpoint. | Posted | | Mean | Standard Deviation | logMAR | | Baseline and Month 30 | | | | ID | Title | Description |
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| OG000 | CNTO 2476 3.0*10^5 Cells | Participants received a single subretinal administration of CNTO 2476 (Palucorcel) comprising 3.0*10^5 cells in 50 microliters (mcL) dosing volume on Day 1. CNTO 2476 was delivered using the custom-designed Delivery System and surgical procedure. |
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| Primary | Change From Baseline in Best Corrected Visual Acuity (BCVA) Total Letters Score at Month 36- Treated Eye | BCVA was assessed in the study eye (Treated eye). BCVA measurements were made using the logMAR visual acuity testing charts. Each letter on the chart has a score value of 0.02 log units. Since there were 5 letters per line, the total score for a line on the logMAR chart represented a change of 0.1 log units. The formula for calculating the logMAR BCVA score was: 1.7 - 0.02*number of letters read. A lower BCVA score indicates better vision. A negative change score indicates improvement. | The safety analysis set defined as participants who were enrolled and received surgery in the study. Here, N (number of participants analyzed) signifies number of participant evaluable for this endpoint. | Posted | | Mean | Standard Deviation | logMAR | | Baseline and Month 36 | | | | ID | Title | Description |
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| OG000 | CNTO 2476 3.0*10^5 Cells | Participants received a single subretinal administration of CNTO 2476 (Palucorcel) comprising 3.0*10^5 cells in 50 microliters (mcL) dosing volume on Day 1. CNTO 2476 was delivered using the custom-designed Delivery System and surgical procedure. |
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| Primary | Change From Baseline in Best Corrected Visual Acuity (BCVA) Total Letters Score at Month 1- Fellow Eye | BCVA was assessed in the fellow eye. BCVA measurements were made using the logMAR visual acuity testing charts. Each letter on the chart has a score value of 0.02 log units. Since there were 5 letters per line, the total score for a line on the logMAR chart represented a change of 0.1 log units. The formula for calculating the logMAR BCVA score was: 1.7 - 0.02*number of letters read. A lower BCVA score indicates better vision. A negative change score indicates improvement. | The safety analysis set defined as participants who were enrolled and received surgery in the study. | Posted | | Mean | Standard Deviation | logMAR | | Baseline and Month 1 | | | | ID | Title | Description |
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| OG000 | CNTO 2476 3.0*10^5 Cells | Participants received a single subretinal administration of CNTO 2476 (Palucorcel) comprising 3.0*10^5 cells in 50 microliters (mcL) dosing volume on Day 1. CNTO 2476 was delivered using the custom-designed Delivery System and surgical procedure. |
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| Primary | Change From Baseline in Best Corrected Visual Acuity Total Letters Score at Month 2- Fellow Eye | BCVA was assessed in the fellow eye. BCVA measurements were made using the logMAR visual acuity testing charts. Each letter on the chart has a score value of 0.02 log units. Since there were 5 letters per line, the total score for a line on the logMAR chart represented a change of 0.1 log units. The formula for calculating the logMAR BCVA score was: 1.7 - 0.02*number of letters read. A lower BCVA score indicates better vision. A negative change score indicates improvement. | The safety analysis set defined as participants who were enrolled and received surgery in the study. | Posted | | Mean | Standard Deviation | logMAR | | Baseline and Month 2 | | | | ID | Title | Description |
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| OG000 | CNTO 2476 3.0*10^5 Cells | Participants received a single subretinal administration of CNTO 2476 (Palucorcel) comprising 3.0*10^5 cells in 50 microliters (mcL) dosing volume on Day 1. CNTO 2476 was delivered using the custom-designed Delivery System and surgical procedure. |
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| Primary | Change From Baseline in Best Corrected Visual Acuity Total Letters Score at Month 3- Fellow Eye | BCVA was assessed in the fellow eye. BCVA measurements were made using the logMAR visual acuity testing charts. Each letter on the chart has a score value of 0.02 log units. Since there were 5 letters per line, the total score for a line on the logMAR chart represented a change of 0.1 log units. The formula for calculating the logMAR BCVA score was: 1.7 - 0.02*number of letters read. A lower BCVA score indicates better vision. A negative change score indicates improvement. | The safety analysis set defined as participants who were enrolled and received surgery in the study. | Posted | | Mean | Standard Deviation | logMAR | | Baseline and Month 3 | | | | ID | Title | Description |
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| OG000 | CNTO 2476 3.0*10^5 Cells | Participants received a single subretinal administration of CNTO 2476 (Palucorcel) comprising 3.0*10^5 cells in 50 microliters (mcL) dosing volume on Day 1. CNTO 2476 was delivered using the custom-designed Delivery System and surgical procedure. |
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| Primary | Change From Baseline in Best Corrected Visual Acuity Total Letters Score at Month 6- Fellow Eye | BCVA was assessed in the fellow eye. BCVA measurements were made using the logMAR visual acuity testing charts. Each letter on the chart has a score value of 0.02 log units. Since there were 5 letters per line, the total score for a line on the logMAR chart represented a change of 0.1 log units. The formula for calculating the logMAR BCVA score was: 1.7 - 0.02*number of letters read. A lower BCVA score indicates better vision. A negative change score indicates improvement. | The safety analysis set defined as participants who were enrolled and received surgery in the study. | Posted | | Mean | Standard Deviation | logMAR | | Baseline and Month 6 | | | | ID | Title | Description |
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| OG000 | CNTO 2476 3.0*10^5 Cells | Participants received a single subretinal administration of CNTO 2476 (Palucorcel) comprising 3.0*10^5 cells in 50 microliters (mcL) dosing volume on Day 1. CNTO 2476 was delivered using the custom-designed Delivery System and surgical procedure. |
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| Primary | Change From Baseline in Best Corrected Visual Acuity Total Letters Score at Month 12- Fellow Eye | BCVA was assessed in the fellow eye. BCVA measurements were made using logMAR visual acuity testing charts. Each letter on the chart has a score value of 0.02 log units. Since there are 5 letters per line, the total score for a line on the logMAR chart represents a change of 0.1 log units. The formula for calculating the logMAR BCVA score is: 1.7 - 0.02*number of letters read. A lower BCVA score indicates better vision. A negative change score indicates improvement. | The safety analysis set defined as participants who were enrolled and received surgery in the study. Here, N (number of participants analyzed) signifies number of participant evaluable for this endpoint. | Posted | | Mean | Standard Deviation | logMAR | | Baseline and Month 12 | | | | ID | Title | Description |
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| OG000 | CNTO 2476 3.0*10^5 Cells | Participants received a single subretinal administration of CNTO 2476 (Palucorcel) comprising 3.0*10^5 cells in 50 microliters (mcL) dosing volume on Day 1. CNTO 2476 was delivered using the custom-designed Delivery System and surgical procedure. |
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| Primary | Change From Baseline in Best Corrected Visual Acuity Total Letters Score at Month 18- Fellow Eye | BCVA was assessed in the fellow eye. BCVA measurements were made using the logMAR visual acuity testing charts. Each letter on the chart has a score value of 0.02 log units. Since there were 5 letters per line, the total score for a line on the logMAR chart represented a change of 0.1 log units. The formula for calculating the logMAR BCVA score was: 1.7 - 0.02*number of letters read. A lower BCVA score indicates better vision. A negative change score indicates improvement. | The safety analysis set defined as participants who were enrolled and received surgery in the study. Here, N (number of participants analyzed) signifies number of participant evaluable for this endpoint. | Posted | | Mean | Standard Deviation | logMAR | | Baseline and Month 18 | | | | ID | Title | Description |
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| OG000 | CNTO 2476 3.0*10^5 Cells | Participants received a single subretinal administration of CNTO 2476 (Palucorcel) comprising 3.0*10^5 cells in 50 microliters (mcL) dosing volume on Day 1. CNTO 2476 was delivered using the custom-designed Delivery System and surgical procedure. |
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| Primary | Change From Baseline in Best Corrected Visual Acuity Total Letters Score at Month 24- Fellow Eye | BCVA was assessed in the fellow eye. BCVA measurements were made using the logMAR visual acuity testing charts. Each letter on the chart has a score value of 0.02 log units. Since there were 5 letters per line, the total score for a line on the logMAR chart represented a change of 0.1 log units. The formula for calculating the logMAR BCVA score was: 1.7 - 0.02*number of letters read. A lower BCVA score indicates better vision. A negative change score indicates improvement. | The safety analysis set defined as participants who were enrolled and received surgery in the study. Here, N (number of participants analyzed) signifies number of participant evaluable for this endpoint. | Posted | | Mean | Standard Deviation | logMAR | | Baseline and Month 24 | | | | ID | Title | Description |
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| OG000 | CNTO 2476 3.0*10^5 Cells | Participants received a single subretinal administration of CNTO 2476 (Palucorcel) comprising 3.0*10^5 cells in 50 microliters (mcL) dosing volume on Day 1. CNTO 2476 was delivered using the custom-designed Delivery System and surgical procedure. |
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| Primary | Change From Baseline in Best Corrected Visual Acuity Total Letters Score at Month 30- Fellow Eye | BCVA was assessed in the fellow eye. BCVA measurements were made using the logMAR visual acuity testing charts. Each letter on the chart has a score value of 0.02 log units. Since there were 5 letters per line, the total score for a line on the logMAR chart represented a change of 0.1 log units. The formula for calculating the logMAR BCVA score was: 1.7 - 0.02*number of letters read. A lower BCVA score indicates better vision. A negative change score indicates improvement. | The safety analysis set defined as participants who were enrolled and received surgery in the study. Here, N (number of participants analyzed) signifies number of participant evaluable for this endpoint. | Posted | | Mean | Standard Deviation | logMAR | | Baseline and Month 30 | | | | ID | Title | Description |
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| OG000 | CNTO 2476 3.0*10^5 Cells | Participants received a single subretinal administration of CNTO 2476 (Palucorcel) comprising 3.0*10^5 cells in 50 microliters (mcL) dosing volume on Day 1. CNTO 2476 was delivered using the custom-designed Delivery System and surgical procedure. |
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| Primary | Change From Baseline in Best Corrected Visual Acuity Total Letters Score at Month 36- Fellow Eye | BCVA was assessed in the fellow eye. BCVA measurements were made using the logMAR visual acuity testing charts. Each letter on the chart has a score value of 0.02 log units. Since there were 5 letters per line, the total score for a line on the logMAR chart represented a change of 0.1 log units. The formula for calculating the logMAR BCVA score was: 1.7 - 0.02*number of letters read. A lower BCVA score indicates better vision. A negative change score indicates improvement. | The safety analysis set defined as participants who were enrolled and received surgery in the study. Here, N (number of participants analyzed) signifies number of participant evaluable for this endpoint. | Posted | | Mean | Standard Deviation | logMAR | | Baseline and Month 36 | | | | ID | Title | Description |
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| OG000 | CNTO 2476 3.0*10^5 Cells | Participants received a single subretinal administration of CNTO 2476 (Palucorcel) comprising 3.0*10^5 cells in 50 microliters (mcL) dosing volume on Day 1. CNTO 2476 was delivered using the custom-designed Delivery System and surgical procedure. |
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| Secondary | Percentage of Participants Losing Greater Than or Equal to (>=) 15 Best Corrected Visual Acuity Letters: Treated Eye | BCVA was assessed as letters read using early treatment diabetic retinopathy study charts and reported as the number of letters read correctly (ranging from 0 to 100 letters) in the study eye (Treated eye). The lower the number of letters read correctly on the eye chart, the worse the vision (or visual acuity). A positive change from baseline indicates an improvement and a negative change from baseline indicates a worsening. The percentage of participants losing >=15 BCVA in the study eye were reported. | The safety analysis set defined as participants who were enrolled and received surgery in the study. Here 'n' (number analyzed) signifies the number of participants who had BCVA data at a visit. | Posted | | Number | | Percentage of Participants | | Months 1, 2 , 3, 6, 12, 18, 24, 30 and 36 | | | | ID | Title | Description |
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| OG000 | CNTO 2476 3.0*10^5 Cells | Participants received a single subretinal administration of CNTO 2476 (Palucorcel) comprising 3.0*10^5 cells in 50 microliters (mcL) dosing volume on Day 1. CNTO 2476 was delivered using the custom-designed Delivery System and surgical procedure. |
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| Secondary | Percentage of Participants Losing >=15 Best Corrected Visual Acuity Letters: Fellow Eye | BCVA was assessed as letters read using early treatment diabetic retinopathy study charts and reported as the number of letters read correctly (ranging from 0 to 100 letters) in the fellow eye. The lower the number of letters read correctly on the eye chart, the worse the vision (or visual acuity). A positive change from baseline indicates an improvement and a negative change from baseline indicates a worsening. The percentage of participants losing >=15 BCVA in the fellow eye were reported. | The safety analysis set defined as participants who were enrolled and received surgery in the study. Here 'n' (number analyzed) signifies the number of participants who had BCVA data at a visit. | Posted | | Number | | Percentage of Participants | | Months 1, 2 , 3, 6, 12, 18, 24, 30 and 36 | | | | ID | Title | Description |
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| OG000 | CNTO 2476 3.0*10^5 Cells | Participants received a single subretinal administration of CNTO 2476 (Palucorcel) comprising 3.0*10^5 cells in 50 microliters (mcL) dosing volume on Day 1. CNTO 2476 was delivered using the custom-designed Delivery System and surgical procedure. |
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| Secondary | Change From Baseline in Best Corrected Visual Acuity Letters at Months 6 and 12: Treated Eye | BCVA was assessed as letters read using early treatment diabetic retinopathy study charts and reported as the number of letters read correctly (ranging from 0 to 100 letters) in the study eye (Treated eye). The lower the number of letters read correctly on the eye chart, the worse the vision (or visual acuity). A positive change from baseline indicates an improvement and a negative change from baseline indicates a worsening. | The safety analysis set defined as participants who were enrolled and received surgery in the study. Here 'n' (number analyzed) signifies the number of participants analyzed at the specified time point. | Posted | | Mean | Standard Deviation | Letters | | Baseline, Months 6 and 12 | | | | ID | Title | Description |
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| OG000 | CNTO 2476 3.0*10^5 Cells | Participants received a single subretinal administration of CNTO 2476 (Palucorcel) comprising 3.0*10^5 cells in 50 microliters (mcL) dosing volume on Day 1. CNTO 2476 was delivered using the custom-designed Delivery System and surgical procedure. |
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| Secondary | Change From Baseline in Best Corrected Visual Acuity at Months 6 and 12: Fellow Eye | BCVA was assessed as letters read using early treatment diabetic retinopathy study charts and reported as the number of letters read correctly (ranging from 0 to 100 letters) in the fellow eye. The lower the number of letters read correctly on the eye chart, the worse the vision (or visual acuity). A positive change from baseline indicates an improvement and a negative change from baseline indicates a worsening. | The safety analysis set defined as participants who were enrolled and received surgery in the study. Here 'n' (number analyzed) signifies the number of participants analyzed at the specified time point. | Posted | | Mean | Standard Deviation | Letters | | Baseline, Months 6 and 12 | | | | ID | Title | Description |
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| OG000 | CNTO 2476 3.0*10^5 Cells | Participants received a single subretinal administration of CNTO 2476 (Palucorcel) comprising 3.0*10^5 cells in 50 microliters (mcL) dosing volume on Day 1. CNTO 2476 was delivered using the custom-designed Delivery System and surgical procedure. |
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| Secondary | Change From Baseline in Growth Rate of Geographic Atrophy (GA) Lesion Area at Months 6 and 12: Treated Eye | The area of GA was determined based primarily on fundus autofluorescence (FAF). The change in GA lesion area was measured by FAF and analysis of FAF images was performed by the central reading center. A positive change from baseline indicates an increase in size of GA lesion area (worsening; disease progression). | The safety analysis set defined as participants who were enrolled and received surgery in the study. Here, N (number of participants analyzed) signifies number of participant evaluable for this endpoint and 'n' (number analyzed) signifies the number of participants analyzed at the specified time point. | Posted | | Mean | Standard Deviation | Square millimeter | | Baseline, Months 6 and 12 | | | | ID | Title | Description |
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| OG000 | CNTO 2476 3.0*10^5 Cells | Participants received a single subretinal administration of CNTO 2476 (Palucorcel) comprising 3.0*10^5 cells in 50 microliters (mcL) dosing volume on Day 1. CNTO 2476 was delivered using the custom-designed Delivery System and surgical procedure. |
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| Secondary | Change From Baseline in Growth Rate of Geographic Atrophy Lesion Area at Months 6 and 12: Fellow Eye | The area of GA was determined based primarily on FAF. The change in GA lesion area was measured by FAF and analysis of FAF images was performed by the central reading center. A positive change from baseline indicates an increase in size of GA lesion area (worsening; disease progression). | The safety analysis set defined as participants who were enrolled and received surgery in the study. Here, N (number of participants analyzed) signifies number of participant evaluable for this endpoint and 'n' (number analyzed) signifies the number of participants analyzed at the specified time point. | Posted | | Mean | Standard Deviation | Square millimeter | | Baseline, Months 6 and 12 | | | | ID | Title | Description |
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| OG000 | CNTO 2476 3.0*10^5 Cells | Participants received a single subretinal administration of CNTO 2476 (Palucorcel) comprising 3.0*10^5 cells in 50 microliters (mcL) dosing volume on Day 1. CNTO 2476 was delivered using the custom-designed Delivery System and surgical procedure. |
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| Secondary | Number of Participants With Treatment-emergent Adverse Events (TEAEs) and Serious Adverse Events (SAEs) | Number of participants with TEAEs and SAEs were assessed. An adverse event (AE) is any untoward medical occurrence in a clinical study participant administered a medicinal (investigational or non investigational) product. An AE does not necessarily have a causal relationship with the treatment and can therefore be any unfavorable and unintended sign (including an abnormal finding), symptom, or disease temporally associated with the use of a medicinal product, whether or not related to that medicinal product. SAE is defined as any untoward medical occurrence that at any dose results in death, Is life-threatening, Requires inpatient hospitalization or prolongation of existing hospitalization, Results in persistent or significant disability/incapacity, Is a congenital anomaly/birth defect, Is a suspected transmission of any infectious agent via a medicinal product. | The safety analysis set defined as participants who were enrolled and received surgery in the study. | Posted | | Count of Participants | | Participants | | Up to Months 36 | | | | ID | Title | Description |
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| OG000 | CNTO 2476 3.0*10^5 Cells | Participants received a single subretinal administration of CNTO 2476 (Palucorcel) comprising 3.0*10^5 cells in 50 microliters (mcL) dosing volume on Day 1. CNTO 2476 was delivered using the custom-designed Delivery System and surgical procedure. |
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| Secondary | Number of Participants With Ocular Treatment-emergent Adverse Events | Number of participants with ocular TEAE were assessed. An AE is any untoward medical occurrence in a clinical study participant administered a medicinal (investigational or non investigational) product. An AE does not necessarily have a causal relationship with the treatment and can therefore be any unfavorable and unintended sign (including an abnormal finding), symptom, or disease temporally associated with the use of a medicinal product, whether or not related to that medicinal product. | The safety analysis set defined as participants who were enrolled and received surgery in the study. | Posted | | Count of Participants | | Participants | | Up to Months 36 | | | | ID | Title | Description |
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| OG000 | CNTO 2476 3.0*10^5 Cells | Participants received a single subretinal administration of CNTO 2476 (Palucorcel) comprising 3.0*10^5 cells in 50 microliters (mcL) dosing volume on Day 1. CNTO 2476 was delivered using the custom-designed Delivery System and surgical procedure. |
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