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| Name | Class |
|---|---|
| Hospital Universitari Joan XXIII de Tarragona. | OTHER |
The purpose of this study is to determine if Reinforcement-Induced Movement Therapy (RIMT), a novel rehabilitation method that augments visuomotor feedback of movements of the patient in virtual reality, is effective in treating hemiparesis resp. learned non-use.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Experimental Group | Experimental | Virtual reality based therapy with augmented visuomotor feedback. |
|
| Control Group | Active Comparator | Virtual reality based therapy without augmentation. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Reinforcement-Induced Movement Therapy (RIMT) | Behavioral | 6 weeks, 1 session a day, 30min per sessions, of physical therapy using a VR rehabilitation gaming system (RGS) with augmented visuomotor feedback |
| Measure | Description | Time Frame |
|---|---|---|
| The upper extremity Fugl-Meyer Assessment | change from baseline in motor function | at baseline, at 6-weeks (after intervention), and at 12-weeks follow-up |
| Measure | Description | Time Frame |
|---|---|---|
| Chedoke Arm Hand Inventory | change from baseline in functional recovery | at baseline, at 6-weeks (after intervention), and at 12-weeks follow-up |
| Barthel Index | change from baseline in activities of daily living |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Rosa Maria San Segundo Mozo, Dra. | Medico Especialista en Medician Fisica y Rehabilitation, Doctora por al Universitat Rovira i Virgili de Tarragona | Principal Investigator |
| Paul F.M.J. Verschure, Prof. | Director SPECS | Study Director |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 10714655 | Background | Ramachandran VS, Rogers-Ramachandran D. Phantom limbs and neural plasticity. Arch Neurol. 2000 Mar;57(3):317-20. doi: 10.1001/archneur.57.3.317. | |
| 7886714 | Background | de Haan RJ, Limburg M, Van der Meulen JH, Jacobs HM, Aaronson NK. Quality of life after stroke. Impact of stroke type and lesion location. Stroke. 1995 Mar;26(3):402-8. doi: 10.1161/01.str.26.3.402. |
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| ID | Term |
|---|---|
| D010291 | Paresis |
| D020521 | Stroke |
| ID | Term |
|---|---|
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| C000727727 | PITX2 protein, human |
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|
| VR-based motor rehabilitation in RGS without augmented feedback | Behavioral | 6 weeks, 1 session a day, 30min per sessions, of physical therapy using a VR rehabilitation gaming system (RGS) |
|
| at baseline, at 6-weeks (after intervention), and at 12-weeks follow-up |
| Hamilton Scale | change from baseline in measurement of depression | at baseline, at 6-weeks (after intervention), and at 12-weeks follow-up |
| 16480566 | Background | Thomas SA, Lincoln NB. Factors relating to depression after stroke. Br J Clin Psychol. 2006 Mar;45(Pt 1):49-61. doi: 10.1348/014466505X34183. |
| 26684921 | Background | Robinson RG, Jorge RE. Post-Stroke Depression: A Review. Am J Psychiatry. 2016 Mar 1;173(3):221-31. doi: 10.1176/appi.ajp.2015.15030363. Epub 2015 Dec 18. |
| 27506203 | Derived | Ballester BR, Maier M, San Segundo Mozo RM, Castaneda V, Duff A, M J Verschure PF. Counteracting learned non-use in chronic stroke patients with reinforcement-induced movement therapy. J Neuroeng Rehabil. 2016 Aug 9;13(1):74. doi: 10.1186/s12984-016-0178-x. |
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |