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the decrease in thoracopulmonary compliance after cardiac surgery is well known . The investigators hypothesize that the major factor determining pulmonary outcome after cardiac surgery is the alteration of pulmonary compliance during cardiopulmonary bypass(CBP) and that this alteration is due to CBP itself through pulmonary blood emptying.
compliance is the compliance calculate when thorax is closed, the pulmonary compliance is the compliance calculated when thorax is opened After operation chest X-ray are daily done and blood samples as needed. Were recorded death, time of extubation,duration of non invasive ventilation,of Intensive Care Unit stay and of total hospital stay, troponin peak, lactates, blood gases, ionogram and count.Variations of compliance is analyzed through one factor paired Anova or Wilcoxon paired test. Decrease of compliance and respiratory complications are analyzed through binomial logistic regression.
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| Measure | Description | Time Frame |
|---|---|---|
| pulmonary compliance during cardiac surgery | compliance is calculated by dividing tidal volume (ml) by the difference between plateau-inspiratory pressure (mmHg) and end-expiratory pressure (mmHg) before ,during and after CBP | intraoperative |
| Measure | Description | Time Frame |
|---|---|---|
| pulmonary complications including death after cardiac surgery | intersticial and/or alveolar pulmonary oedema leading to death or extra hospital stay | 1 month |
| thoracopulmonary compliance during cardiac surgery |
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Inclusion Criteria:
Exclusion Criteria:
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Every ASA 2 or 3 patient eligible for non-complex and non-urgent cardiac surgery
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre Chirurgical Marie Lannelongue | Le Plessis-Robinson | 92350 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 6024032 | Background | Ellison LT, Duke JF 3rd, Ellison RG. Pulmonary compliance following open-heart surgery and its relationship to ventilation and gas exchange. Circulation. 1967 Apr;35(4 Suppl):I217-25. doi: 10.1161/01.cir.35.4s1.i-217. No abstract available. | |
| 340159 | Background | Suter PM, Fairley HB, Isenberg MD. Effect of tidal volume and positive end-expiratory pressure on compliance during mechanical ventilation. Chest. 1978 Feb;73(2):158-62. doi: 10.1378/chest.73.2.158. |
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compliance is calculated by dividing tidal volume (ml) by the difference between peak-inspiratory pressure (mmHg) and end-expiratory pressure (mmHg) before ,during and after CBP
| intraoperative |