Ketorolac Sublingual vs. Fentanyl Intranasal in Pain Control for Bilateral Myringotomy and Tubes (BMT) Placement in Children

Prospective, Randomized, Allocation-Concealed, Blinded Study Designed to Compare Ketorolac Sublingual and Fentanyl Intranasal in Pain Control for Bilateral Myringotomy and Tubes (BMT) Placement in Children

The purpose of this study is to compare the efficacy and safety of ketorolac sublingual with fentanyl intranasal used in our hospital for pain control in children undergoing bilateral myringotomy with placement of pressure equalization tubes (BMTs).

This prospective, randomized, allocation concealed blinded study is designed to compare ketorolac sublingual vs. fentanyl intranasal vs. the combination of these two medications for pain control after BMTs in children. Bilateral myringotomy and tube placement is an elective operation, mainly in the pediatric population.

Inclusion Criteria:

• American Society of Anesthesiologist (ASA) I-II physical class
• Scheduled for elective BMT
• Mask induction of anesthesia

Exclusion Criteria:

• Allergy to any NSAIDs
• Severe upper respirator infection
• Severe asthma
• Bleeding disorders
• History of GI bleeding
• Renal impairment
• Scheduled for one-sided myringotomy and tube placement