Dietary Supplement on Symptom Awareness and Heart Rhythm in Patients With Cardiac Arrhythmia

Influence of a Specific Micronutrient Combination on Symptom Awareness and Heart Rhythm in Patients With Cardiac Arrhythmia

The main aim of this study, which was carried out in two parallel groups, is testing the efficacy of a specific micronutrients combination in adults with heart rhythm disturbances and accompanying symptoms.

It is therefore the investigators hypothesis that daily oral administration of the specific micronutrients combination will lead to a decrease of symptoms awareness and to a reduction of heart rhythm disturbances in adults with or without structural heart disease. The principal endpoints will be a decrease in the total score of symptoms awareness.

Inclusion Criteria:

• PVB in the long-term ECG recording (registration at least 18 hours): at least 500 PVB/24 h or Supraventricular tachycardia (≥10 episodes/24h, outside sporting activity) or SVPB with vegetative symptoms (increased sweating, inner unrest, shaky hands, red dermographism) and no cardial pretreatment

Exclusion Criteria:

• Left ventricular ejection fraction [EF] ≤ 40 %
• Therapy with spironolactone > 50 mg/d
• Therapy with torasemide > 20 mg/d
• Supplementation or therapy with dietary supplements or drugs which contain vitamins and minerals (above all potassium and magnesium)
• Creatinine in the serum [i. S.]:≥ 1,4 mg/dl (men), ≥ 1,2 mg/dl (women)
• Potassium i. S. ≤ 3,4 mmol/l and > 5,4 mmol/l
• Magnesium i. S. ≤ 0,7 mmol/l and > 1,0 mmol/l
• Acute and chronic diarrhea
• Hyperthyroidism anamnestic or due to the current TSH (thyroid stimulating hormone)-value
• Pacemaker