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The embryo transfer implies transportation from the incubator where they have been at 37 ° C, to the transfer catheter inside a laminar flow hood whose working surface is also maintained at 37 ° C. . From the laboratory to the operating room the embryo is exposed to a temperature drop, and consequently thermal stress occurs, which may compromise its future viability.
The aim of this study is to assess the possible improvement in the clinical results when the embryos are transported in a stable device to avoid the drop in temperature throughout the transfer process.
With the use of this thermosetting device heated to 37 ° C, researchers expect a 15% increase in pregnancy rates.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Conventional transfer | No Intervention | This arm is the control group (conventional embryo transfer protocol) where there is no intervention. | |
| Thermostable device transfer | Experimental | This arm is the study group: embryo transfer protocol using a new thermostable device. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Thermostable device | Device | Investigators place the catheter with the loaded embryos into a plastic device at 37ºC in order to maintain the temperature |
|
| Measure | Description | Time Frame |
|---|---|---|
| Ongoing Pregnancy rate | Achieving an ongoing pregnancy after embryo transfer | Ongoing pregnancy until 28th week of gestation |
| Measure | Description | Time Frame |
|---|---|---|
| Miscarriage rate | To know the embryonic loss rate after implantation | Loss of pregnancy up to 12 weeks of gestation |
| Implantation rate | To know the embryo implantation rate after the embryo transfer |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jorge Ten Morro, Ph.D. | Contact | 696914882 | jten@institutobernabeu.com | |
| Jorge Ten Morro, Ph.D | Contact | 696914882 | jten@institutobernabeu.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Instituto Bernabeu | Recruiting | Alicante | 03016 | Spain |
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| Embryo implantation after 6-7 weeks of gestation |