Single-cycle Remote Ischemic Preconditioning and Postconditioning (SCRIP) Trial

Effect of Single-cycle Remote Ischemic Preconditioning and Postconditioning on Myocardial Injury in Patients Undergoing Emergency and Elective Percutaneous Intervention in Phramongkutklao Hospital and Thammasat University

This trial is a 2 x 2 factorial design, double-blinded, randomized controlled trial to evaluate efficacy and safety of remote ischemic preconditioning and postconditioning in patient undergoing coronary angioplasty.

Inclusion Criteria:

• Eligible for percutaneous coronary intervention (elective and emergency cases)
• Age > 18-year-old
• Informed consent

Exclusion Criteria:

• Previous CABG
• Previous PCI in 1 week / treatment with thrombolysis within 30 days
• Peripheral arterial disease / A-V shunt of upper extremities (AVF for hemodialysis)
• Paresis of upper limb
• Unstable patient such as cardiogenic shock / vasopressor / IABP / cooling (hypothermia)
• Fatal cardiac arrhythmia (VT / VF)
• Chronic hypoxia